Evidence map›Paper›PMID 28126841›Full record

ArticleDevelopment (Cambridge, England)2017

Regulatory logic driving stable levels of

Jenny Yan, Caitlin Anderson, Kayla Viets, Sang Tran, Gregory Goldberg, Stephen Small, Robert J Johnston

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Deep conservation complemented by novelty and innovation in the insect eye ground plan.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Transcriptional priming and chromatin regulation during stochastic cell fate specification.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  5. Article
  6. The power of the (imperfect) palindrome: Sequence-specific roles of palindromic motifs in gene regulation.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022
    Review
  7. Article
  8. Enhancer redundancy in development and disease.Nature reviews. Genetics · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Post-Transcriptional Noise Control.BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jenny YanDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218-2685, USA.
Caitlin AndersonDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218-2685, USA.
Kayla VietsDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218-2685, USA.
Sang TranDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218-2685, USA.
Gregory GoldbergCenter for Developmental Genetics, Department of Biology, New York University, 100 Washington Square East, New York, NY 10003-6688, USA.
Stephen SmallCenter for Developmental Genetics, Department of Biology, New York University, 100 Washington Square East, New York, NY 10003-6688, USA.
Robert J JohnstonDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218-2685, USA robertjohnston@jhu.edu.ORCID 0000-0002-5775-6218

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Mechanisms controlling stochastic gene expression during eye developmentR01EY025598 · NEI · JOHNS HOPKINS UNIVERSITY · PI Robert John Johnston · 2015 to 2026
$4.9M
Regulatory Logic of a Transcription Factor Family in two Developmental ContextsR01GM106090 · NIGMS · NEW YORK UNIVERSITY · PI SMALL, STEPHEN J · 2014 to 2017
$1.4M
Determining the role of 3D nuclear architecture in stochastic gene expressionF31EY026786 · NEI · JOHNS HOPKINS UNIVERSITY · PI VIETS, KAYLA CHELSEA · 2016 to 2018
$88k
NEI NIH HHS F31 EY026786NEI NIH HHS R01 EY025598NIGMS NIH HHS R01 GM106090NIGMS NIH HHS T32 GM007231
6 · The paper itself

Abstract

How differential levels of gene expression are controlled in post-mitotic neurons is poorly understood. In the

Indexed as

Cell DifferentiationEnhancer Elements, GeneticGene Expression Regulation, DevelopmentalAnimalsDrosophila melanogasterDrosophila ProteinsGreen Fluorescent ProteinsHomeodomain ProteinsHomeostasisMitosisNeuronsPhotoreceptor Cells, InvertebrateProventriculusRetinaRhodopsinTranscription FactorsDrosophila ProteinsGreen Fluorescent ProteinsHomeodomain ProteinsRhodopsinTranscription FactorsDark shadow enhancerDefective proventriculusDrosophila retinaOrthodenticlePhotoreceptorRhodopsinShadow enhancerSpaltSpineless

Identifiers

PMID28126841
PMCPMC5374349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.