Evidence map›Paper›PMID 28126203›Full record

ArticleJournal of autoimmunity2017

Skin-derived TSLP systemically expands regulatory T cells.

Theresa M Leichner, Atsushi Satake, Victor Sanoe Harrison, Yukinori Tanaka, Angela S Archambault, Brian S Kim, Mark C Siracusa, Warren J Leonard, Ali Naji, Gregory F Wu and 2 more

Abstract read
In one paragraph

Article in Journal of autoimmunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. TSLP: contrasting roles in cancer.Frontiers in immunology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Human Lung Mast Cells: Therapeutic Implications in Asthma.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Theresa M LeichnerDepartment of Pathology & Laboratory Medicine, University of Pennsylvania, United States.
Atsushi SatakeFirst Department of Internal Medicine, Kansai Medical University, Japan.
Victor Sanoe HarrisonDepartment of Pediatrics, Children's Hospital of Philadelphia, United States.
Yukinori TanakaDepartment of Pathology & Laboratory Medicine, University of Pennsylvania, United States.
Angela S ArchambaultDepartment of Neurology, Washington University School of Medicine, United States.
Brian S KimDivision of Dermatology, Department of Medicine, Department of Anesthesiology, Department of Pathology and Immunology, Center for the Study of Itch, United States.
Mark C SiracusaCenter for Immunity and Inflammation, Department of Medicine, New Jersey Medical School, Rutgers-The State University of New Jersey, United States.
Warren J LeonardNational Institutes of Health, United States.
Ali NajiDepartment of Surgery, University of Pennsylvania, United States.
Gregory F WuDepartment of Neurology, Washington University School of Medicine, United States.
David ArtisDepartment of Medicine, Weill Cornell Medical College, United States.
Taku KambayashiDepartment of Pathology & Laboratory Medicine, University of Pennsylvania, United States. Electronic address: taku.kambayashi@uphs.upenn.edu.
University of Pennsylvania · USChildren's Hospital of Philadelphia · USCornell University · USKansai Medical University · JPNational Institutes of Health · USRutgers New Jersey Medical School

Funding

IL-2 Family Cytokines and their Receptors--Biology of the IL-7/TSLP SystemsZIAHL005409 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEONARD, WARREN J · 2009 to 2025
$10.0M
Translational Research Training in Pediatric Diabetes & EndocrinologyT32DK063688 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI LORRAINE E LEVITT KATZ, ANDREA Bridget KELLY · 2002 to 2026
$5.4M
The role of the T cell receptor in regulatory T cell homeostasis and expansionR01HL111501 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAMBAYASHI, TAKU · 2012 to 2020
$3.6M
Proximal signaling complexes in NK cell effector function and developmentR01HL107589 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAMBAYASHI, TAKU · 2011 to 2015
$2.0M
ROLE OF B CELL ANTIGEN PRESENTATION IN AUTOIMMUNE ENCEPHALOMYELITISR01NS083678 · NINDS · WASHINGTON UNIVERSITY · PI WU, GREGORY · 2013 to 2017
$1.7M
NHLBI NIH HHS R01 HL107589NHLBI NIH HHS R01 HL111501NIDDK NIH HHS T32 DK063688NINDS NIH HHS R01 NS083678
6 · The paper itself

Abstract

Regulatory T cells (Tregs) are a subset of CD4

Indexed as

AnimalsBiomarkersCholecalciferolCytokinesDiabetes Mellitus, ExperimentalEncephalomyelitis, Autoimmune, ExperimentalLymphocyte ActivationLymphocyte CountMiceMice, KnockoutMice, TransgenicModels, BiologicalSignal TransductionSkinThymic Stromal LymphopoietinT-Lymphocytes, RegulatoryBiomarkersCholecalciferolCytokinesThymic Stromal LymphopoietinTSLP protein, mouseImmunotherapyRegulatory T cellsThymic stromal lymphopoietinToleranceVitamin D

Identifiers

PMID28126203
PMCPMC5386815
OpenAlexW2579992807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.