Evidence map›Paper›PMID 28126032›Full record

ArticleBMC health services research2017

Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework.

Mandeep Sekhon, Martin Cartwright, Jill J Francis

28 registry-linked trialsAbstract read
In one paragraph

Article in BMC health services research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 28 registered trials, which are not on this map. Cited by 2,105 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,105citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03689049 naactive not recruitingnot on this mapstarted 2018, after this paper: background citation

SPIDER: A Structured Process Informed by Data, Evidence and Research - A Research and Quality Improvement Collaboration Supporting Practices in Improving Care for Complex Elderly Patients

TypeinterventionalSponsorUniversity of Toronto Practice Based Research NetworkRan2018 to 2027Enrolled104ConditionsPolypharmacy, Inappropriate Prescribing, Aged, Primary Health CareArmsSPIDER, Usual Care
NCT03788122 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Qualitative In-depth Interviews With Women and Their Partners Concerning the Acceptability of Fetal Surgery

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2018 to 2026Enrolled40ConditionsFetal Surgery, Myelomeningocele, Congenital Diaphragmatic HerniaArmsIn-depth interview
NCT03791008 nacompletednot on this mapstarted 2019, after this paper: background citation

Personalized Breast Cancer Screening: Assessment of Its Feasibility and Acceptability in the National Health System

TypeinterventionalSponsorInstitut de Recerca Biomèdica de LleidaRan2019 to 2021Enrolled387ConditionsBreast CancerArmsRisk based screening
NCT04420546 nacompletednot on this mapstarted 2020, after this paper: background citation

Using Implementation Intentions to Reduce Self-harm

TypeinterventionalSponsorUniversity of ManchesterRan2020 to 2021Enrolled1,040ConditionsSelf-HarmArmsVolitional help sheet
NCT04671225 nacompletednot on this mapstarted 2021, after this paper: background citation

Psychoeducation for Patients With Bipolar Disorder in Rwanda

TypeinterventionalSponsorUniversity of AarhusRan2021 to 2022Enrolled154ConditionsBipolar DisorderArmsGroups Psychoeducation, Waiting-list
NCT05225376 nacompletednot on this mapstarted 2022, after this paper: background citation

Physical Activity and Sedentary Lifestyle During Pregnancy: Feasibility and Impact Study on Sedentary Behavior

TypeinterventionalSponsorUniversity Hospital, Clermont-FerrandRan2022 to 2023Enrolled25ConditionsSedentary Behavior, Pregnancy Related, Perinatal Problems, Sedentary TimeArmsPhysical activity sessions for pregnant women
NCT05368701 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Randomised Controlled Trial of a Smartphone-based App to Reduce Self-harm for CAMHS-treated Adolescents

TypeinterventionalSponsorUniversity of ManchesterRan2022 to 2023Enrolled90ConditionsSelf-harmArmsVolitional Help Sheet for self-harm
NCT05444504 narecruitingnot on this mapstarted 2023, after this paper: background citation

Effectiveness and Acceptability of Two Insertable Device Models for Non-surgical Management of Obstetric Fistula: a Randomized Crossover Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2026Enrolled100ConditionsObstetric Fistula, Fistula, Fistula, Urinary, Fistula, VaginalArmsCup, Cup+
NCT05545904 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Pilot Study to Evaluate the Feasibility & Acceptability of a Peer-mentor Delivered Substance Use Screening and Brief Intervention for Adolescents in Kenya

TypeinterventionalSponsorMoi UniversityRan2023 to 2024Enrolled60ConditionsSubstance UseArmsSubstance use brief intervention (BI), substance use education intervention
NCT05587517 phase2recruitingnot on this mapstarted 2022, after this paper: background citation

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2022 to 2027Enrolled172ConditionsGrief, Trauma, Psychotherapy, Critical CareArmsEMPOWER, Supportive Conversation
NCT05830188 nacompletednot on this mapstarted 2023, after this paper: background citation

Feasibility, Acceptability, and Effectiveness of a Coping and Resilience Intervention in Adolescents in the Post-COVID-19 Era

TypeinterventionalSponsorTaipei Medical UniversityRan2023 to 2023Enrolled110ConditionsCOVID-19 PandemicArmsCoping and Resilience Intervention for Adolescents, Printing materials of Coping and Resilience Intervention for Adolescents
NCT06022809 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparative Effectiveness of Individual Versus Group-level Interventions to Reduce HIV Risk Among African Immigrant Women

TypeinterventionalSponsorMassachusetts General HospitalRan2023 to 2026Enrolled149ConditionsHIV, Other STIsArmsDada Kwa Dada (individual-level), DADA (group-level)
NCT06216639 unknown statusnot on this mapstarted 2024, after this paper: background citation

EU4Health Project Eurohelican: A Single-center Prospective Feasibility Study of the Proposed Test-and-treat Preventive Screening Program in Younger Slovenian Participants Aged 30-34 Years With or Without Helicobacter Pylori Infection

TypeobservationalSponsorNational Institute of Public Health, SloveniaRan2024 to 2025Enrolled2,000ConditionsHelicobacter Pylori InfectionArmsBismuth Subcitrate, Esomeprazole, Metronidazole, Amoxicillin, Clarithromycin
NCT06225531 nacompletednot on this mapstarted 2024, after this paper: background citation

Exploring the Feasibility and Acceptability of an Autobiographical Memory-Based Intervention for People With Suicidality: A Case Series

TypeinterventionalSponsorLancaster UniversityRan2024 to 2024Enrolled3ConditionsSuicidal Ideation, Mental Health DisorderArmsAutobiographical Memory Based Intervention
NCT06567340 narecruitingnot on this mapstarted 2025, after this paper: background citation

StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression

TypeinterventionalSponsorRotherham Doncaster and South Humber NHS Foundation TrustRan2025 to 2027Enrolled1,252ConditionsDepressionArmsStratCare
NCT06596031 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Health Coaching in Addition to a Digital Resource to Promote Self-management for Patients Waiting for Total Hip or Knee Replacements: A Randomised Feasibility Trial

TypeinterventionalSponsorSheffield Hallam UniversityRan2025 to 2025Enrolled36ConditionsArthritis Knee, Arthritis of HipArmsHealth coaching, Digital toolkit
NCT06624358 narecruitingnot on this mapstarted 2025, after this paper: background citation

Physical Activity in Adolescents With Chronic Kidney Disease

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2025 to 2028Enrolled100ConditionsChronic Kidney DiseasesArmsIncrease Physical Activity
NCT06963086 narecruitingnot on this mapstarted 2026, after this paper: background citation

Implementing an Eating Disorder Prevention Program for Youth in Nova Scotia

TypeinterventionalSponsorSusan GambergRan2026 to 2026Enrolled120ConditionsBody Image, Body Dissatisfaction, Dietary Restraint, Negative AffectArmsEating disorder prevention program (the Body Project)
NCT07027813 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility and Efficacy of Ambulance-Based m-Health for Pediatric Emergencies in Low Resource Settings (FEAMER) Trial

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2025 to 2026Enrolled900ConditionsEmergencies, mHealth, Child Health, Critical IllnessArmsTelemedicine, Control
NCT07041528 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

How Do Patients and Health Care Professionals Perceive De-implementation of Routine Follow-ups After Total Hip and Knee Arthroplasty? Protocol for a Nested Qualitative Study Within a Hybrid De-implementation Trial

TypeobservationalSponsorTergooi Medical CenterRan2026 to 2028Enrolled90ConditionsHip Arthroplasty, Total, Knee Arthroplasty, Total
NCT07418723 nacompletednot on this mapstarted 2024, after this paper: background citation

Personalised Process-based Psychological Intervention for Paediatric Headache Cases: An Idiographic Ecological Momentary Study With Weekly Feedback Provision

TypeinterventionalSponsorRoyal Holloway UniversityRan2024 to 2025Enrolled5ConditionsPrimary Headaches (Includes Migraines, Tension, Cluster Headaches)ArmsPBT Personalised
NCT07420881 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Start 4 All - DARE-TB

TypeinterventionalSponsorLiverpool School of Tropical MedicineRan2026 to 2027Enrolled60,000ConditionsTB - TuberculosisArmsNear point of care (NPOC) NAATs, Low-complexity nucleic acid amplification tests (LC-NAATs), LC-NAAT using pooled testing, Computer-Aided Detection (CAD) Chest X-ray (CXR-AI), Culture (reference standard)
NCT07456670 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Caffeine Therapy in Preterm Infants Born at 28-34 Weeks: A Pilot Placebo-Controlled Randomized Controlled Trial

TypeinterventionalSponsorQueen's UniversityRan2026 to 2028Enrolled62ConditionsPreterm Birth, Caffeine, Neonatal OutcomesArmsCaffeine, Placebo
NCT07517471 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Start4All - Start Taking Action for TB Diagnosis SCREEN-TB

TypeinterventionalSponsorLiverpool School of Tropical MedicineRan2026 to 2027Enrolled37,000ConditionsTB - TuberculosisArmsNear point of care (NPOC) NAATs, Low-complexity nucleic acid amplification tests (LC-NAATs), LC-NAAT using pooled testing, Portable Chest X-ray Image Acquisition, Computer-Aided Detection (CAD) Chest X-ray (CXR-AI)
NCT07603219 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility And Acceptability of a Nurse-Led Educational Intervention for Caregivers of ICU Patients (Nurses For Family - N4F): Pilot Study

TypeinterventionalSponsorMedical University of GdanskRan2026 to 2027Enrolled20ConditionsCaregiver, ICU PatientsArmsNurse-Led Educational Intervention for Caregivers of ICU Patients (Nurses For Family - N4F)
NCT07636408 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Enhancing Sleep to Improve Brain-heart Functions in People With Persistent Post-concussion Symptoms

TypeinterventionalSponsorUniversity of OttawaRan2026 to 2027Enrolled70ConditionsInsomnia, Concussion Post SyndromeArmsCBT-pI, Sleep Hygiene
NCT07712263 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Integrating the Guardian Spatial Emanator Within AVENIR II

TypeinterventionalSponsorUniversity of California, San FranciscoRan2026 to 2028Enrolled150,000ConditionsMalariaArmsSpatial Emanator
NCT07751107 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Early Virtual Ankle Rehabilitation (EVAR): A Proof-of-concept Feasibility Study Exploring Patient Acceptability Using Qualitative Interviews With Nested Quantitative Analysis.

TypeinterventionalSponsorUniversity of NottinghamRan2026 to 2027Enrolled30ConditionsAnkle FractureArmsEVAR, EMADE
3 · Its place in the literature

Who cites it

2,105 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Statins for adults with a first episode of venous thromboembolic disease.The Cochrane database of systematic reviews · 2026
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2,045 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Mandeep SekhonCity, University of London, Northampton Square, London, EC1V 0JB, UK. Mandeep.sekhon.1@city.ac.uk.ORCID 0000-0002-5109-9536
Martin CartwrightCity, University of London, Northampton Square, London, EC1V 0JB, UK.
Jill J FrancisCity, University of London, Northampton Square, London, EC1V 0JB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is increasingly acknowledged that 'acceptability' should be considered when designing, evaluating and implementing healthcare interventions. However, the published literature offers little guidance on how to define or assess acceptability. The purpose of this study was to develop a multi-construct theoretical framework of acceptability of healthcare interventions that can be applied to assess prospective (i.e. anticipated) and retrospective (i.e. experienced) acceptability from the perspective of intervention delivers and recipients.

methodsTwo methods were used to select the component constructs of acceptability. 1) An overview of reviews was conducted to identify systematic reviews that claim to define, theorise or measure acceptability of healthcare interventions. 2) Principles of inductive and deductive reasoning were applied to theorise the concept of acceptability and develop a theoretical framework. Steps included (1) defining acceptability; (2) describing its properties and scope and (3) identifying component constructs and empirical indicators.

resultsFrom the 43 reviews included in the overview, none explicitly theorised or defined acceptability. Measures used to assess acceptability focused on behaviour (e.g. dropout rates) (23 reviews), affect (i.e. feelings) (5 reviews), cognition (i.e. perceptions) (7 reviews) or a combination of these (8 reviews). From the methods described above we propose a definition: Acceptability is a multi-faceted construct that reflects the extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention. The theoretical framework of acceptability (TFA) consists of seven component constructs: affective attitude, burden, perceived effectiveness, ethicality, intervention coherence, opportunity costs, and self-efficacy.

conclusionDespite frequent claims that healthcare interventions have assessed acceptability, it is evident that acceptability research could be more robust. The proposed definition of acceptability and the TFA can inform assessment tools and evaluations of the acceptability of new or existing interventions.

Indexed as

ConsensusModels, TheoreticalPatient Acceptance of Health CareHumansProspective StudiesRetrospective StudiesReview Literature as TopicAcceptabilityComplex interventionDefining constructsHealthcare interventionTheory development

Identifiers

PMID28126032
PMCPMC5267473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.