Evidence map›Paper›PMID 28125965›Full record

ArticleBMC family practice2017

Microbiological point of care testing before antibiotic prescribing in primary care: considerable variations between practices.

Steffen Haldrup, Reimar W Thomsen, Flemming Bro, Robert Skov, Lars Bjerrum, Mette Søgaard

Open access · goldAbstract read
In one paragraph

Article in BMC family practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Steffen HaldrupDepartment of Clinical Epidemiology, Aarhus University, Olof Palmes Alle 43-45, 8200, Aarhus N, Denmark. steffenhaldrup@au.dk.
Reimar W ThomsenDepartment of Clinical Epidemiology, Aarhus University, Olof Palmes Alle 43-45, 8200, Aarhus N, Denmark.
Flemming BroDepartment of General Practice, Institute of Public Health, Aarhus University, Aarhus, Denmark.
Robert SkovAntimicrobial Resistance Reference Laboratory and Surveillance Unit, Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark.
Lars BjerrumSection and Research Unit of General Practice, Department of Public Health, Copenhagen University, Copenhagen, Denmark.
Mette SøgaardDepartment of Clinical Epidemiology, Aarhus University, Olof Palmes Alle 43-45, 8200, Aarhus N, Denmark. mette.soegaard@rn.dk.
Aarhus University · DKStatens Serum Institut · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoint-of-care testing (POCT) in primary care may improve rational antibiotic prescribing. We examined use of POCT in Denmark, including patient- and general practitioner (GP)-related predictors.

methodsWe linked nationwide health care databases to assess POCT use (C-reactive protein (CRP), group A streptococcal (GAS) antigen swabs, bacteriological cultures, and urine test strips) per 1,000 overall GP consultations, 2004-2013. We computed odds ratios (OR) of POCT in patients prescribed antibiotics according to patient and GP age and sex, GP practice type, location, and workload.

resultsThe overall use of POCT in Denmark increased by 45.8% during 2004-2013, from 147.2 per 1,000 overall consultations to 214.8. CRP tests increased by 132%, bacteriological cultures by 101.7% while GAS swabs decreased by 8.6%. POCT preceded 28% of antibiotic prescriptions in 2004 increasing to 44% in 2013. The use of POCT varied more than 5-fold among individual practices, from 54.9 to 394.7 per 1,000 consultations in 2013. POCT use varied substantially with patient age, and males were less likely to receive POCT than females (adjusted OR = 0.75, 95% CI 0.74-0.75) driven by usage of urine test strips among females (18% vs. 7%). Odds of POCT were higher among female GPs and decreased with higher GP age, with lowest usage among male GPs >60 years. GP urban/rural location and workload had little impact.

conclusionGPs use POCT increasingly with the highest use among young female GPs. In 2013, 44% of all antibiotic prescriptions were preceded by POCT but testing rates vary greatly across individual GPs.

Indexed as

General PractitionersPractice Patterns, Physicians'Primary Health CareAdolescentAdultAgedAged, 80 and overAge FactorsAnti-Bacterial AgentsBacterial InfectionsChildChild, PreschoolC-Reactive ProteinCross-Sectional StudiesCulture TechniquesDenmarkAnti-Bacterial AgentsC-Reactive ProteinAntibioticGeneral practiceInfectionPoint-of-care

Identifiers

PMID28125965
PMCPMC5270219
OpenAlexW2581121124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.