Evidence map›Paper›PMID 28125649›Full record

ArticlePLoS neglected tropical diseases2017

Investigation of a Medieval Pilgrim Burial Excavated from the Leprosarium of St Mary Magdalen Winchester, UK.

Simon Roffey, Katie Tucker, Kori Filipek-Ogden, Janet Montgomery, Jamie Cameron, Tamsin O'Connell, Jane Evans, Phil Marter, G Michael Taylor

Open access · goldAbstract readHistorical Article
In one paragraph

Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Ancient DNA confirmation of lepromatous leprosy in a skeleton with concurrent osteosarcoma, excavated from the leprosarium of St. Mary Magdalen in Winchester, Hants., UK.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  3. Article
  4. Article
  5. One Health Approaches to TraceFrontiers in microbiology · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Simon RoffeyDepartment of Archaeology, University of Winchester, Winchester, United Kingdom.ORCID 0000-0002-6400-126X
Katie TuckerDepartment of Archaeology, University of Winchester, Winchester, United Kingdom.
Kori Filipek-OgdenDepartment of Archaeology, Durham University, Durham United Kingdom.
Janet MontgomeryDepartment of Archaeology, Durham University, Durham United Kingdom.
Jamie CameronResearch Laboratory for Archaeology and the History of Art, University of Oxford, Dyson Perrins Building, Oxford, United Kingdom.
Tamsin O'ConnellMcDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge, United Kingdom.
Jane EvansNERC Isotope Geosciences Laboratory, Keyworth, Notts, United Kingdom.
Phil MarterDepartment of Archaeology, University of Winchester, Winchester, United Kingdom.
G Michael TaylorDepartment of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, AX Building, University of Surrey, Guildford, Surrey, United Kingdom.
University of Winchester · GBDurham University · GBUniversity of Cambridge · GBUniversity of Oxford · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have examined the remains of a Pilgrim burial from St Mary Magdalen, Winchester. The individual was a young adult male, aged around 18-25 years at the time of death. Radiocarbon dating showed the remains dated to the late 11th-early 12th centuries, a time when pilgrimages were at their height in Europe. Several lines of evidence in connection with the burial suggested this was an individual of some means and prestige. Although buried within the leprosarium cemetery, the skeleton showed only minimal skeletal evidence for leprosy, which was confined to the bones of the feet and legs. Nonetheless, molecular testing of several skeletal elements, including uninvolved bones all showed robust evidence of DNA from Mycobacterium leprae, consistent with the lepromatous or multibacillary form of the disease. We infer that in life, this individual almost certainly suffered with multiple soft tissue lesions. Genotyping of the M.leprae strain showed this belonged to the 2F lineage, today associated with cases from South-Central and Western Asia. During osteological examination it was noted that the cranium and facial features displayed atypical morphology for northern European populations. Subsequently, geochemical isotopic analyses carried out on tooth enamel indicated that this individual was indeed not local to the Winchester region, although it was not possible to be more specific about their geographic origin.

Indexed as

Bone and BonesDNA, BacterialGenotypeHistory, MedievalHumansLeprosyMaleMycobacterium lepraeOsteologyUnited KingdomYoung AdultDNA, Bacterial

Identifiers

PMID28125649
PMCPMC5268360
OpenAlexW2580312418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.