ArticleMMWR. Morbidity and mortality weekly report2017
Cluster of an Unusual Amnestic Syndrome - Massachusetts, 2012-2016.
Article in MMWR. Morbidity and mortality weekly report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurocognitive impairments and brain abnormalities resulting from opioid-related overdoses: A systematic review.Drug and alcohol dependence · 2021Pooled it
- Hippocampal Volume and Brain Tau Pathology in Opioid Use Disorder: Associations with Non-Fatal Opioid Overdose.Addiction neuroscience · 2026Article
- Regular use of opioids and dementia, cognitive measures, and neuroimaging outcomes among UK Biobank participants with chronic non-cancer pain.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Histopathologic correlates of opioid-associated injury in CHANTER syndrome: first report of a post-mortem examination.Acta neuropathologica · 2024Article
- CHANTER syndrome in the context of pain medication: a case report.BMC neurology · 2024Article
- Toxic-Induced Encephalopathy Following Chemsex in a Young HIV-Positive Male: A Complex Case of Acute Cognitive Impairment with Anterograde Amnesia and Behavioral Alterations.Infectious diseases and therapy · 2024Article
- Is there a relationship between opioid use and transient global amnesia?European journal of neurology · 2024Article
- Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in the setting of opioid and phencyclidine use.Radiology case reports · 2023Article
- Hippocampal volume loss in individuals with a history of non-fatal opioid overdose.Addiction biology · 2023Article
- Hippocampal and Cerebellar Involvement in Opioid-Associated Amnestic Syndrome: A Unique Case Report.Cureus · 2023Article
- Association between toxic drug events and encephalopathy in British Columbia, Canada: a cross-sectional analysis.Substance abuse treatment, prevention, and policy · 2023Article
- Bilateral hippocampal toxic damage: an "unforgettable" cause of acute global amnesia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Potential Relationship Between Polysubstance Overdose, Hypoxia, and Increased Risk of Delayed Leukoencephalopathy.The Neurohospitalist · 2023Article
- Diffuse subcortical white matter restriction: An uncommon finding on metronidazole toxicity.The neuroradiology journal · 2023Article
- Forgetting the Unforgettable: Transient Global Amnesia Part II: A Clinical Road Map.Journal of clinical medicine · 2022Review
- Bilateral Acute Hippocampal Ischemia in Two Patients Abusing Cocaine: What is the Outcome?Cureus · 2022Article
- Detecting risk level in individuals misusing fentanyl utilizing posts from an online community on Reddit.Internet interventions · 2021Article
- Time-Dependent Changes in the Serum Levels of Neurobiochemical Factors After Acute Methadone Overdose in Adolescent Male Rat.Cellular and molecular neurobiology · 2021Article
- Amnestic Syndrome and Bilateral Hippocampal Diffusion Abnormalities From Opioid Use.Neurology. Clinical practice · 2021Article
- Opioid-Associated Amnestic Syndrome.Cureus · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In November 2015, a neurologist in the Boston, Massachusetts, area reported four cases of an uncommon amnestic syndrome involving acute and complete ischemia of both hippocampi, as identified by magnetic resonance imaging (MRI), to the Massachusetts Department of Public Health (MDPH) (1). A subsequent e-mail alert, generated by the Massachusetts Board of Registration in Medicine and sent to relevant medical specialists (including neurologists, neuroradiologists, and emergency physicians), resulted in the identification of 10 additional cases that had occurred during 2012-2016. All 14 patients (mean and median age = 35 years) had been evaluated at hospitals in eastern Massachusetts. Thirteen of the 14 patients underwent routine clinical toxicology screening at the time of initial evaluation; eight tested positive for opioids, two for cocaine, and two for benzodiazepines. Apart from sporadic cases (2-6), this combination of clinical and imaging findings has been reported rarely. The apparent temporospatial clustering, relatively young age at onset (19-52 years), and associated substance use among these patients should stimulate further case identification to determine whether these observations represent an emerging syndrome related to substance use or other causes (e.g., a toxic exposure).
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