Trial reportEmerging infectious diseases2017
Successful Treatment of Human Plague with Oral Ciprofloxacin.
Trial report in Emerging infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- A systematic review of the clinical profile of patients with bubonic plague and the outcome measures used in research settings.PLoS neglected tropical diseases · 2023Pooled it
- Antimicrobial Treatment and Prophylaxis of Plague: Recommendations for Naturally Acquired Infections and Bioterrorism Response.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Guideline
- Ciprofloxacin versus Aminoglycoside-Ciprofloxacin for Bubonic Plague.The New England journal of medicine · 2025Trial
- A Decade of Antimicrobial Resistance in Human and AnimalAntibiotics (Basel, Switzerland) · 2024Review
- Harnessing Graphene-Modified Electrode Sensitivity for Enhanced Ciprofloxacin Detection.International journal of molecular sciences · 2024Article
- Bubonic plague: can the size of buboes be accurately and consistently measured with a digital calliper?Trials · 2023Article
- Plague Gives Surprises in the Second Decade of the Twenty-First Century.The American journal of tropical medicine and hygiene · 2023Article
- Clinical and Translational Pharmacology Considerations for Anti-infectives Approved Under the FDA Animal Rule.Clinical pharmacokinetics · 2023Review
- Towards Antibiotic Synthesis in Continuous-Flow Processes.Molecules (Basel, Switzerland) · 2023Review
- The impact of COVID-19 on clinical research for Neglected Tropical Diseases (NTDs): A case study of bubonic plague.PLoS neglected tropical diseases · 2021Article
- Review
- Finafloxacin Is an Effective Treatment for Inhalational Tularemia and Plague in Mouse Models of Infection.Antimicrobial agents and chemotherapy · 2021Article
- Antibiotic Therapy of Plague: A Review.Biomolecules · 2021Review
- Yersinia pestis: the Natural History of Plague.Clinical microbiology reviews · 2020Review
- Article
- Human plague: An old scourge that needs new answers.PLoS neglected tropical diseases · 2020Review
- Antimicrobial Treatment Patterns and Illness Outcome Among United States Patients With Plague, 1942-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Mixed pneumonic plague and nosocomial MDR-bacterial infection of lung: a rare case report.BMC pulmonary medicine · 2018Article
- Patterns of Human Plague in Uganda, 2008-2016.Emerging infectious diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.