ArticleJournal of perinatology : official journal of the California Perinatal Association2017
Maternal body mass index and spontaneous contractility of human myometrium in pregnancy.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Maternal Body Mass Index, Myometrium Contractility and Uterotonic Receptor Expression in Pregnancy.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Article
- The Pathophysiology of Labor Dystocia: Theme with Variations.Reproductive sciences (Thousand Oaks, Calif.) · 2023Review
- Forces Involved with Labor and Delivery-A Biomechanical Perspective.Annals of biomedical engineering · 2021Review
- Adiponectin links maternal metabolism to uterine contractility.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Article
- Maternal parity and functional contractility of human myometrium in vitro in the third trimester of pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Influence of maternal exercise on fetal heart response during labor and delivery.Health science reports · 2018Article
- Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development.Journal of visualized experiments : JoVE · 2018Article
- Unchanged mitochondrial phenotype, but accumulation of lipids in the myometrium in obese pregnant women.The Journal of physiology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere is controversy as to whether maternal body mass index (BMI) influences the contractility of human myometrium in pregnancy. The aim of this study was to examine spontaneous contractile activity of human pregnant myometrium in vitro, with respect to maternal BMI. STUDY
designMyometrial tissue specimens were obtained at cesarean delivery from 74 women with BMI values ranging from 19 to 50.1 kg m
resultsThere was a significant correlation between maximum amplitude (P=0.007) and mean contractile force (P=0.001) with increasing BMI. However, the time to onset of contractions (P=0.009), and time taken to reach maximal amplitude (P=0.020) also increased with increasing BMI. No significant correlation was observed with BMI for other parameters studied. The mean maximum amplitude value for spontaneous contractions was 37±1 mN, the mean contractile force for spontaneous contractions was 4.1±0.1 mN, the average time to the first spontaneous contraction was 11.3±0.6 min and the average frequency of contractions was 6.5±0.2 per hour.
conclusionsThese results suggest that the time to onset of contractions is increased with increasing maternal BMI, but that the force developed is greater. In all other respects, human uterine contractility is unaffected by increasing BMI. These findings underline the complexity of regulation of uterine contractility in labor with elevated maternal BMI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.