Evidence map›Paper›PMID 28125032›Full record

ReviewInternational journal of environmental research and public health2017

Malpighian Tubules as Novel Targets for Mosquito Control.

Peter M Piermarini, Carlos J Esquivel, Jerod S Denton

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A single-cell atlas of thebioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. TargetingViruses · 2023
    Review
  12. Malpighian tubules ofFrontiers in insect science · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Activation of mosquito immunity blocks the development of transmission-stage filarial nematodes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Peter M PiermariniDepartment of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA. piermarini.1@osu.edu.
Carlos J EsquivelDepartment of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA. esquivelpalma.1@buckeyemail.osu.edu.
Jerod S DentonDepartments of Anesthesiology and Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA. jerod.s.denton@Vanderbilt.Edu.
The Ohio State University · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Malpighian tubules and hindgut are the renal excretory tissues of mosquitoes; they are essential to maintaining hemolymph water and solute homeostasis. Moreover, they make important contributions to detoxifying metabolic wastes and xenobiotics in the hemolymph. We have focused on elucidating the molecular mechanisms of Malpighian tubule function in adult female mosquitoes and developing chemical tools as prototypes for next-generation mosquitocides that would act via a novel mechanism of action (i.e., renal failure). To date, we have targeted inward rectifier potassium (Kir) channels expressed in the Malpighian tubules of the yellow fever mosquito

Indexed as

AedesAnimalsAnophelesFemaleMalariaMalpighian TubulesMosquito ControldetoxificationhomeostasisinsecticidesMalpighian tubulesmosquito, Kir channelssmall molecule

Identifiers

PMID28125032
PMCPMC5334665
OpenAlexW2582687758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.