ReviewJournal of clinical medicine2017
Mechanisms of Regulatory B cell Function in Autoimmune and Inflammatory Diseases beyond IL-10.
Review in Journal of clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- B Cells or T Cells in the Development and Sustenance of Rheumatoid Arthritis: Who is the Potential Contributor?Mediterranean journal of rheumatology · 2026Review
- Serum Inflammatory Factors Levels and Risk of Myasthenia Gravis: A Bidirectional Mendelian Randomization Study.Molecular neurobiology · 2025Article
- Elevated frequencies of activated memory B cells in multiple sclerosis are reset to healthy control levels after B cell depletion with Ocrelizumab.Journal of neuroimmunology · 2025Article
- Dynamic roles of tumor-infiltrating B lymphocytes in cancer immunotherapy.Cancer immunology, immunotherapy : CII · 2025Review
- Mesenchymal stem cells for immune modulation in systemic lupus erythematosus: From bench research to clinical applications.Narra J · 2024Review
- Two distinct subpopulations of marginal zone B cells exhibit differential antibody-producing capacities and radioresistance.Cellular & molecular immunology · 2024Article
- B cell subsets contribute to myocardial protection by inducing neutrophil apoptosis after ischemia and reperfusion.JCI insight · 2024Article
- Breg-Mediated Immunoregulation in the Skin.International journal of molecular sciences · 2024Review
- Differentially activated B cells develop regulatory phenotype and show varying immunosuppressive features: a comparative study.Frontiers in immunology · 2023Article
- Circulating Regulatory B-Lymphocytes in Patients with Acute Myocardial Infarction: A Pilot Study.Journal of cardiovascular development and disease · 2022Article
- Skin-Homing Regulatory B Cells Required for Suppression of Cutaneous Inflammation.The Journal of investigative dermatology · 2021Article
- Discovery and Function of B-Cell IgD Low (BDJournal of molecular biology · 2021Review
- Characterization of Definitive Regulatory B Cell Subsets by Cell Surface Phenotype, Function and Context.Frontiers in immunology · 2021Review
- Possible Role of Regulatory B Cells in Different Behçet's Disease Phenotypes and Therapies: First Report from Egypt.Journal of inflammation research · 2021Article
- Real-world data combined with studies on Regulatory B Cells for newly diagnosed Multiple Myeloma from a tertiary referral Hospital in South-Western China.Journal of Cancer · 2021Article
- The frequency of follicular T helper cells differs in acute and chronic neuroinflammation.Scientific reports · 2020Article
- Toll-Like Receptor Signaling and Immune Regulatory Lymphocytes in Periodontal Disease.International journal of molecular sciences · 2020Review
- Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance.Annals of the New York Academy of Sciences · 2020Review
- Cytokine profiling in anti neutrophil cytoplasmic antibody-associated vasculitis: a cross-sectional cohort study.Rheumatology international · 2019Article
- EBV Latency III-Transformed B Cells Are Inducers of Conventional and Unconventional Regulatory T Cells in a PD-L1-Dependent Manner.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In the past two decades it has become clear that in addition to antigen presentation and antibody production B cells play prominent roles in immune regulation. While B cell-derived IL-10 has garnered much attention, B cells also effectively regulate inflammation by a variety of IL-10-independent mechanisms. B cell regulation has been studied in both autoimmune and inflammatory diseases. While collectively called regulatory B cells (Breg), no definitive phenotype has emerged for B cells with regulatory potential. This has made their study challenging and thus unique B cell regulatory mechanisms have emerged in a disease-dependent manner. Thus to harness the therapeutic potential of Breg, further studies are needed to understand how they emerge and are induced to evoke their regulatory activities.
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Registered trials
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