Evidence map›Paper›PMID 28124972›Full record

ArticleeLife2017

Selecting the most appropriate time points to profile in high-throughput studies.

Michael Kleyman, Emre Sefer, Teodora Nicola, Celia Espinoza, Divya Chhabra, James S Hagood, Naftali Kaminski, Namasivayam Ambalavanan, Ziv Bar-Joseph

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Article
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  7. Article
  8. Review
  9. Review
  10. Optimal experimental design for mathematical models of haematopoiesis.Journal of the Royal Society, Interface · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Integrating multiomics longitudinal data to reconstruct networks underlying lung development.American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. LungMAP: The Molecular Atlas of Lung Development Program.American journal of physiology. Lung cellular and molecular physiology · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael KleymanMachine Learning and Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, United States.
Emre SeferMachine Learning and Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, United States.
Teodora NicolaDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, United States.
Celia EspinozaDivision of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, United States.
Divya ChhabraDivision of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, United States.
James S HagoodDivision of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, United States.
Naftali KaminskiSection of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, Yale University, New Haven, United States.
Namasivayam AmbalavananDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, United States.
Ziv Bar-JosephMachine Learning and Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, United States.ORCID 0000-0003-3430-6051

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FAEDER, JAMES · 2012 to 2021
$16.3M
Integrated Interdisciplinary, inter-university PhD Program Computational Biology (T32)T32EB009403 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHAR, IVET, BAR-JOSEPH, ZIV · 2009 to 2023
$4.4M
Alveolar DevMAPU01HL122626 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMBALAVANAN, NAMASIVAYAM, HAGOOD, JAMES S. · 2014 to 2018
$3.7M
NHLBI NIH HHS U01 HL122626NIGMS NIH HHS P41 GM103712
6 · The paper itself

Abstract

Biological systems are increasingly being studied by high throughput profiling of molecular data over time. Determining the set of time points to sample in studies that profile several different types of molecular data is still challenging. Here we present the Time Point Selection (

Indexed as

AnimalsGene Expression ProfilingHigh-Throughput Nucleotide SequencingLungMiceTime Factorscomputational biologyexperimental designlung developementmousesystems biologytime point selection

Identifiers

PMID28124972
PMCPMC5319842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.