Evidence map›Paper›PMID 28124779›Full record

ArticleJournal of microbiology (Seoul, Korea)2017

A lactic acid bacterium isolated from kimchi ameliorates intestinal inflammation in DSS-induced colitis.

Jin-Soo Park, Inseong Joe, Paul Dong Rhee, Choon-Soo Jeong, Gajin Jeong

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of microbiology (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. ProbioticPreventive nutrition and food science · 2024
    Article
  3. Article
  4. Fermented foods and gastrointestinal health: underlying mechanisms.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Are Fermented Foods Effective against Inflammatory Diseases?International journal of environmental research and public health · 2023
    Review
  9. Kimchi andFoods (Basel, Switzerland) · 2023
    Article
  10. Lactobacillus plantarum strains attenuated DSS-induced colitis in mice by modulating the gut microbiota and immune response.International microbiology : the official journal of the Spanish Society for Microbiology · 2022
    Article
  11. Journal of microbiology and biotechnology · 2022
    Article
  12. Article
  13. Comparison of the Probiotic Potential betweenFoods (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Article
  16. Protective Effect ofFoods (Basel, Switzerland) · 2020
    Article
  17. Regulatory Effect ofFoods (Basel, Switzerland) · 2020
    Article
  18. Article
  19. Clinical & translational immunology · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin-Soo ParkDepartment of Biological Science, University of Ulsan, Ulsan, 44610, Republic of Korea.
Inseong JoeFranklin W. Olin College of Engineering, Needham, MA, USA.
Paul Dong RheeSchool of Biological Sciences, College of Natural Science, Seoul National University, Seoul, 08826, Republic of Korea.
Choon-Soo JeongDepartment of Biological Science, University of Ulsan, Ulsan, 44610, Republic of Korea. csjeong@ulsan.ac.kr.
Gajin JeongSchool of Biological Sciences, College of Natural Science, Seoul National University, Seoul, 08826, Republic of Korea. jeongg@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some species of lactic acid bacteria have been shown to be beneficial in inflammatory bowel disease (IBD). In the present study, a strain of lactic acid bacterium (Lactobacillus paracasei LS2) was isolated from the Korean food, kimchi, and was shown to inhibit the development of experimental colitis induced by dextran sulfate sodium (DSS). To investigate the role of LS2 in IBD, mice were fed DSS in drinking water for seven days along with LS2 bacteria which were administered intragastrically to some of the mice, while phosphate-buffered saline (PBS) was administered to others (the controls). The administration of LS2 reduced body weight loss and increased survival, and disease activity indexes (DAI) and histological scores indicated that the severity of colitis was significantly reduced. The production of inflammatory cytokines and myeloperoxidase (MPO) activity also decreased. Flow cytometry analysis showed that the number of Th1 (IFN-γ) population cells was significantly reduced in the LS2-administered mice compared with the controls. The administration of LS2 induced the increase of CD4

Indexed as

AnimalsBody WeightColitisCytokinesDextran SulfateDisease Models, AnimalFlow CytometryFood MicrobiologyHistocytochemistryImmunophenotypingLacticaseibacillus paracaseiMacrophagesMiceNeutrophilsPeroxidaseProbioticsCytokinesDextran SulfatePeroxidasedextran sulfate sodiuminflammatory bowel diseasekimchilactic acid bacteria

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.