ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Cystometric analysis of the transplanted bladder.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Strategies of Bladder Reconstruction after Partial or Radical Cystectomy for Bladder Cancer.Molecular biotechnology · 2025Review
- Introducing a novel experimental model of bladder transplantation in mice.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Article
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Abstract
objectivecystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. MATERIAL AND
methodstwo groups were constituted: (A) bladder autotransplant with two subgroups: R1 - (control) and R2 - (bladder transplant); (B) isogeneic bladder transplant with three subgroups; T1 - (control); T2-T3, two subgroups observed for 30 and 60 days after transplant, respectively. All animals underwent cystometric evaluation. Afterwards, the bladders were removed for histological study.
resultsthe transplanted bladders did not show significant changes in filling/storage and emptying/micturition functions after 30 and 60 days of evolution. Upon macroscopical evaluation, there was good revascularization and the tissue was well preserved. Cystometry results: did not show significant differences in the micturition pressure in subgroups T2-T3, but did between subgroups R1-R2, T1-T2, and T1-T3. Significant differences were verified in the micturition interval between T1-T3, T2-T3, but not between R1-R2, T1-T2. There was significant difference in the micturition duration between T1-T3 but not between R1-R2, T1-T2 and T2-T3. No fistula was noted on the suture site nor leakage of urine in the abdominal cavity or signs of necrosis or retraction were observed.
conclusionstransplant of the bladder was shown to be a viable procedure. The results indicate that there was structural and functional regeneration of transplanted bladders, and these results indicate that it is possible that vascular endothelium growth and neurogenesis factors are involved and activated in the process of the preservation or survival of the transplanted organ.
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