Observational studyHernia : the journal of hernias and abdominal wall surgery2017
Preoperative progressive pneumoperitoneum and botulinum toxin type A in patients with large incisional hernia.
Observational study in Hernia : the journal of hernias and abdominal wall surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Outcomes of anterior component separation versus posterior component separation with transversus abdominis muscle release for large incisional hernias: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Systematic review and meta-analysis of the pre-operative application of botulinum toxin for ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- Is there a role for botulinum toxin A in the emergency setting for delayed abdominal wall closure in the management of the open abdomen? A systematic review.Annals of the Royal College of Surgeons of England · 2023Pooled it
- A systematic review of the use of progressive preoperative pneumoperitoneum since its inception.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- A traction suture for abdominal wall closure in large incisional hernias: a prospective analysis of the "suitcase technique" - a simple horizontal offloading z-suture for gradual myofascial approximation.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Ultrasound alone is sufficient: no added value of electromyography in botulinum toxin prehabilitation for complex ventral hernias?Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- Patient Experience and Surgical Outcomes of Botulinum Toxin A Treatment in Complex Abdominal Wall Hernias: A Retrospective Analysis.Journal of abdominal wall surgery : JAWS · 2026Article
- Advances in Intestinal Restoration and Abdominal Wall Reconstruction in Bogotá: A Two-Stage Approach During the Same Hospitalization.Journal of abdominal wall surgery : JAWS · 2026Article
- Preoperative Botulinum Toxin A (BTA) injection in abdominal wall reconstruction for subxiphoid (M1) hernias.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Repair of Giant Parastomal Hernia with Loss of Domain by Total Colectomy: A Case Report.Surgical case reports · 2025Article
- Mesh-Augmented Ventral Hernia Repair Despite IatrogenicSurgical case reports · 2025Article
- Editorial: Components Separation Techniques in Abdominal Wall Surgery.Journal of abdominal wall surgery : JAWS · 2025Article
- Complications related to the prehabilitation with preoperative pneumoperitoneum in loss of domain hernias: our experience in 180 consecutive cases.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- Anterior versus posterior component separation technique for advanced abdominal wall reconstruction: a proposed algorithm.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Exploring Variable Approaches in Complex Hernia Repair: A Comprehensive Literature Review.Cureus · 2024Review
- Botulinum Toxin and Progressive Pneumoperitoneum in Loss of Domain Ventral Hernias: A Systematic Review.Journal of abdominal wall surgery : JAWS · 2024Review
- [Loss of domain and reduction in median suture tension].Chirurgie (Heidelberg, Germany) · 2024Review
- Article
- Preoperative Progressive Pneumoperitoneum in the Treatment of Hernias With Loss of Domain. Our Experience in 50 Cases.Journal of abdominal wall surgery : JAWS · 2023Article
- Simultaneous Treatment of Complex Incisional Hernia and Stoma Reversal.Journal of abdominal wall surgery : JAWS · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCombination of preoperative progressive pneumoperitoneum (PPP) and botulinum toxin type A (BT) has not been previously reported in the management of large incisional hernia (LIH).
methodsObservational study of 45 consecutive patients with LIH between June 2010 and July 2014. The diameters of the hernia sac, the volumes of the incisional hernia (VIH) and the abdominal cavity (VAC), and the VIH/VAC ratio were measured before and after PPP and BT using abdominal CT scan data. We indicated the combination of both techniques when the volume of the incisional hernia (VIH)/volume of the abdominal cavity (VAC) ratio was >20%.
resultsThe median insufflated volume of air for PPP was 8.600 ± 3.200 cc (4.500-13.250), over a period of 14.3 ± 1.3 days (13-16). BT administration time was 40.2 ± 3.3 days (37-44). We obtained an average value of reduction of 14% of the VIH/VAC ratio after PPP and BT (p < 0.05). Complications associated with PPP were 15.5%, and with surgical technique, 26.6%. No complications occurred during the BT administration. Reconstructive technique was anterior CST and primary fascial closure was achieved in all patients. Median follow-up was 40.5 ± 19 months (12-60) and we reported 2 cases of hernia recurrence (4.4%).
conclusionsPreoperative combination of PPP and BT is feasible and a useful tool in the surgical management of LIH, although at the cost of some specific complications.
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