Evidence map›Paper›PMID 28124202›Full record

ReviewCurrent treatment options in gastroenterology2017

Pyloric Therapies for Gastroparesis.

Nitin K Ahuja, John O Clarke

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03126513 nacompletednot on this map

Safety and Efficacy of Gastric Per Oral Endoscopic Myotomy (G-POEM) in Patients With Refractory Gastroparesis

TypeinterventionalSponsorCoordinación de Investigación en Salud, MexicoRan2017 to 2021Enrolled82ConditionsGastroparesis Postoperative, Gastroparesis Due to Diabetes Mellitus, Idiopathic Gastric StasisArmsG-POEM
NCT06173336 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

A Randomized Controlled Prospective Trial Comparing Clinical Outcomes and Efficacy of Single vs. Double Pyloromyotomy Technique for Gastric Peroral Endoscopic Pyloromyotomy (G-POEM) in the Treatment of Gastroparesis

TypeinterventionalSponsorUniversity of ArkansasRan2025 to 2025Enrolled0ConditionsGastroparesisArmsgastric per-oral endoscopic myotomy (G-POEM)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Role of Endoscopy in Motility Disorders of Upper Gastrointestinal Tract.Journal of neurogastroenterology and motility · 2023
    Review
  3. Review
  4. Review
  5. Gastroparesis in the 2020s: New Treatments, New Paradigms.Current gastroenterology reports · 2020
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Outcomes of combined pyloric botulinum toxin injection and balloon dilation in dyspepsia with and without delayed gastric emptying.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nitin K AhujaDivision of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John O ClarkeDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, 300 Pasteur Drive Room H0206B, CA, MC 5244, Standford, USA. jclarke2@stanford.edu.
Johns Hopkins Medicine · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementGastroparesis is a syndrome that can be difficult to treat effectively and likely represents the common clinical presentation of multiple underlying mechanisms. One of these presumed mechanisms involves pyloric dysfunction, tied perhaps to spasm or fibrosis, manifesting as functional gastric outlet obstruction. Various diagnostic modalities have been used to better characterize this hypothesized abnormality, including most recently antroduodenal manometry and impedance planimetry. A variety of therapeutic interventions specific to the pylorus have also been proposed in the last several years, including intrapyloric injections of botulinum toxin, transpyloric stenting, surgical pyloroplasty, and endoscopic pyloromyotomy. The clinical application of these maneuvers has been mostly empiric thus far, but efforts are ongoing to identify the subset of patients whose physiology best positions them to benefit from such therapy. Early results for many of these interventions have been promising and will serve as the basis for larger and more systematic research frameworks moving forward.

Indexed as

BotoxG-PoemPyloromyotomyPyloroplastyPylorospasmStent

Identifiers

PMID28124202
OpenAlexW2582011022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.