ArticleParasitology research2017
Diagnosis of Strongyloides stercoralis by morphological characteristics combine with molecular biological methods.
Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Prevalence of strongyloidiasis in immunocompromised patients in Mazandaran province of northern Iran: A comprehensive study utilizing simultaneous parasitological, serological, and molecular techniques.Parasite epidemiology and control · 2025Article
- From past to present: opportunities and trends in the molecular detection and diagnosis of Strongyloides stercoralis.Parasites & vectors · 2023Review
- A Rare Case ofPathogens (Basel, Switzerland) · 2023Article
- Strongyloides stercoralis Infection in a Patient with Chronic Renal Failure from North China.Acta parasitologica · 2021Article
- Chronic strongyloidiasis: a case of B symptoms and recurrent asthma exacerbations.BMJ case reports · 2020Article
- Descriptive Investigation of Strongyloidiasis Infection and Characterization ofCase reports in infectious diseases · 2020Article
- Fatty acid and retinol-binding protein: A novel antigen for immunodiagnosis of human strongyloidiasis.PloS one · 2019Article
- Strongyloides stercoralis larvae found for the first time in tap water using a novel culture method.Parasitology research · 2018Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strongyloidiasis is one of the neglected tropical diseases caused by infection with the nematode Strongyloides genus and distributed worldwide. Strongyloidiasis can be fatal in immunosuppressed patients induced hyperinfection or disseminated strongyloidiasis. Unfortunately, until now, due to the unspecific clinical symptom in infected individuals and the low sensitivity diagnosis of strongyloidiasis, many patients were misdiagnosed every year. Furthermore, the larvae of the Strongyloides stercoralis (S. stercoralis) is similar to other nematodes such as hookworm, Trichostrongylus increased the difficulty of diagnosis. In this case, the patient is a 63-year-old male person, who had a nearly 30 years medical history of asthma and emphysema, and 4-5-year medical history of diabetes. The sputum examination found some parasite larvae, then we identify the larvae using clinical observation and morphological characteristics combine with examined cytochrome oxidase subunit 1 (COX1) and 18S rRNA genes by PCR, sequence analysis and finally classified by phylogenetic analysis, the larvae were diagnosed as S. stercoralis. Our results showed that diagnosis with strongyloidiasis by morphological characteristics combine with molecular biological methods can improve the sensitive of diagnosis and provide a final diagnosis for the disease in the clinics.
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