Evidence map›Paper›PMID 28124112›Full record

ArticleWorld journal of urology2017

Is there room for behavioral and modifiable health-related targets in the lower urinary tract symptoms' scenario.

Osamu Ikari, Brunno C F Sanches, João Carlos Cardoso Alonso, Fabiano A Simões, Ronald F Rejowski, Walker Wendel Laranja, Leonardo O Reis

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Article in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Correlation of tools for objective evaluation of infravesical obstruction of men with lower urinary tract symptoms.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Osamu IkariUniversity of Campinas, Unicamp, São Paulo, Brazil.
Brunno C F SanchesUniversity of Campinas, Unicamp, São Paulo, Brazil.
João Carlos Cardoso AlonsoPaulínia Municipal Hospital, São Paulo, Brazil.
Fabiano A SimõesPaulínia Municipal Hospital, São Paulo, Brazil.
Ronald F RejowskiPaulínia Municipal Hospital, São Paulo, Brazil.
Walker Wendel LaranjaPaulínia Municipal Hospital, São Paulo, Brazil.
Leonardo O ReisUrologic Oncology, Faculty of Medicine, Center for Life Sciences, Pontifical Catholic University of Campinas (PUC-Campinas), Campinas, São Paulo, Brazil. reisleo.l@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo better understand potential modifiable risk factors guiding preventive interventions against lower urinary tract symptoms (LUTS).

methodsA prospective cross-sectional study, including healthy men aged 40-70 years under routine urological evaluation, measured the strength of association between the International Prostate Symptom Score (IPSS) and socio-demographic, lifestyle, and health-related factors using logistic and linear regression adjusted for confounding factors. Men with urethral or prostate surgery were excluded.

resultsAmong 743 men, mean age 59.64 ± 9.66, 22.6% reported moderate, and 5.0% severe LUTS. The adjusted odds of severe LUTS increased with: increasing age (OR = 1.07, 95% CI = 1.05-1.09, p < .0001), increasing prostate volume (OR = 1.02, 95% CI = 1.01-1.04, p = .004), decreasing education (tertiary qualification, no versus yes, OR = 2.34; 95% CI = 1.16-4.70; p = .0133), delayed ejaculation (yes versus no, OR = 2.63, 95% CI = 1.43-4.83, p < .0001), and increasing blood pressure (systolic ≥130 mmHg, OR = 2.03, 95% CI = 1.44-2.86, p < .0001 or diastolic ≥85 mmHg, OR = 1.47, 95% CI = 1.03-2.10, p = .0345); severe LUTS decreased with: increasing the weekly sexual frequency (OR = 0.80, 95% CI = 0.69-0.91, p = .0012) and increasing HDL cholesterol (OR = 0.98, 95% CI = 0.97-0.99, p = .037). Odds were not significant for age of sexual initiation, precocious ejaculation, masturbatory pattern, physical activity, smoking, alcohol consumption, penile length (objective and subjective), abdominal circumference, obesity, comorbid conditions, metabolic syndrome, serum glycaemia, testosterone, SHBG, PSA, and estradiol.

conclusionsOne in every four men under routine urological evaluation who considered themselves healthy present moderate and severe LUTS. Modifiable behavioral (education, sexual frequency, and ejaculation) and health-related (blood pressure and HDL cholesterol) targets were identified for future interventional studies and potential preventive actions and patient counseling.

Indexed as

Blood PressureEducational StatusAdultAgedAlcohol DrinkingBlood GlucoseCholesterol, HDLCross-Sectional StudiesEjaculationEstradiolExerciseHumansKallikreinsLinear ModelsLogistic ModelsLower Urinary Tract SymptomsBlood GlucoseCholesterol, HDLEstradiolKallikreinsKLK3 protein, humanProstate-Specific AntigenSex Hormone-Binding GlobulinTestosteroneChronic pelvic ischemia syndromeIPSSRisk factorVoiding

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.