Evidence map›Paper›PMID 28124103›Full record

SynthesisInternational orthopaedics2017

Surgical treatment of infected shoulder arthroplasty. A systematic review.

Giulio Maria Marcheggiani Muccioli, Gazi Huri, Alberto Grassi, Tommaso Roberti di Sarsina, Giuseppe Carbone, Enrico Guerra, Edward G McFarland, Mahmut N Doral, Maurilio Marcacci, Stefano Zaffagnini

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Giulio Maria Marcheggiani MuccioliDipartimento Rizzoli Sicilia, Istituto Ortopedico Rizzoli, University of Bologna, via di Barbiano, 1/10 - c/o Lab Biomeccanica ed Innovazione Tecnologica, 40136, Bologna, Italy. marcheggianimuccioli@me.com.
Gazi HuriDepartment of Sports Medicine, University of Hacettepe, Ankara, Turkey.
Alberto GrassiDipartimento Rizzoli Sicilia, Istituto Ortopedico Rizzoli, University of Bologna, via di Barbiano, 1/10 - c/o Lab Biomeccanica ed Innovazione Tecnologica, 40136, Bologna, Italy.
Tommaso Roberti di SarsinaII Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
Giuseppe CarboneII Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
Enrico GuerraDivision of Shoulder Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy.
Edward G McFarlandDivision of Shoulder Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Mahmut N DoralDepartment of Sports Medicine, University of Hacettepe, Ankara, Turkey.
Maurilio MarcacciII Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
Stefano ZaffagniniDipartimento Rizzoli Sicilia, Istituto Ortopedico Rizzoli, University of Bologna, via di Barbiano, 1/10 - c/o Lab Biomeccanica ed Innovazione Tecnologica, 40136, Bologna, Italy.
Istituto Ortopedico Rizzoli · ITHacettepe University · TRUniversity of Bologna · ITJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the best surgical management of infected shoulder arthroplasty.

methodsA literature review from 1996 to 2016 identified 15 level IV studies that met inclusion criteria. Persistent infection (PI) was considered as treatment failure. Success was regarded as the absence of symptomatic PI without necessity for further treatment. Surgical outcomes were reported according to the mean weighted Constant and Murley score (CMS) for each treatment group.

resultsOverall, 287 patients (146 males/141 females) were identified at a mean follow-up of 50.4 (range 32-99.6) months. The PI in the whole population was 11.5%. The pooled mean CMS, available for 218 patients, was 39 ± 13. Twenty-seven patients (9.4%) were treated with debridement (PI 29.6%, CMS 41 ± 12), 52 patients (18.1%) with resection arthroplasty (PI 11.5%, CMS 29 ± 16), 33 patients (11.5%) with permanent spacers (PI 6.1%, CMS 31 ± 14), 98 patients (34.2%) with two-stage revisions (PI 14.3%, CMS 42 ± 12) and 77 patients (26.8%) with one-stage revisions (PI 3.9%, CMS 49 ± 11). Debridement showed the highest PI rate (29.6%) and one-stage revisions reported the lowest PI rate (3.9%). Resection arthroplasty and spacers showed the poorest CMS when compared to the other procedures (p ≤ 0.0001). The debridement PI rate was significantly higher than almost any other procedure. CMS was significantly higher in patients undergoing revision compared to non-revision procedures (45 ± 12 vs. 35 ± 14) (p < 0.0001). One-stage revisions achieved significantly better results in terms of the PI rate compared to two-stage revisions (p = 0.0223), but not in terms of CMS.

conclusionDebridement showed the highest PI rate (29.6%) and should not be recommended for the management of infected shoulder arthroplasty. Revisions reported better functional outcomes compared to non-revision procedures. The presence of a significantly lower PI rate with comparablely high mean CMS values suggests that one-stage (where technically applicable) could be superior to two-stage revisions. Unfortunately, well-designed randomized controlled trials using validated patient-based outcomes are lacking in this field. LEVEL OF EVIDENCE: Systematic Review of level IV studies, Level IV.

Indexed as

Arthroplasty, Replacement, ShoulderHumansProsthesis-Related InfectionsShoulder JointArthroplastyInfectionShoulderSurgical treatmentSystematic review

Identifiers

PMID28124103
OpenAlexW2581166218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.