ArticlePeerJ2017
Comparison of different sample preparation methods for platinum determination in cultured cells by graphite furnace atomic absorption spectrometry.
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Determination of Trace Platinum in Water Samples by Ionic Liquid-Dispersive Liquid-Liquid Microextraction Combined with Graphite Furnace Atomic Absorption Spectrometry.Molecules (Basel, Switzerland) · 2026Article
- Assessment of Heavy Metals and Related Impacts on Antioxidants and Physiological Parameters in Oil Refinery Workers in Iraq.Journal of health & pollution · 2021Article
- Chloroxine overrides DNA damage tolerance to restore platinum sensitivity in high-grade serous ovarian cancer.Cell death & disease · 2021Article
- Effects of Single Nucleotide Polymorphism Ala270Ser (rs316019) on the Function and Regulation of hOCT2.Biomolecules · 2019Article
- Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.Cancer science · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlatinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection of intracellular platinum is pivotal for studies aiming to overcome platinum resistance. In the present study, we aimed to establish a reliable graphite furnace atomic absorption spectrometry (GFAAS)-based assay to quantify the intracellular platinum content for cultured cells.
methodsSeveral most commonly applied cell preparation methods, including 0.2% HNO
resultsThe treatment of cells with 0.2% HNO DISCUSSION: After comparison, we found that 0.2% HNO
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