Evidence map›Paper›PMID 28123868›Full record

ArticleOncoimmunology

The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.

Roberta Melchionna, Pierluigi Iapicca, Francesca Di Modugno, Paola Trono, Isabella Sperduti, Matteo Fassan, Ivana Cataldo, Borislav C Rusev, Rita T Lawlor, Maria Grazia Diodoro and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Correlation between S100A11 and the TGF-βMolecular and cellular biochemistry · 2019
    Article
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  16. hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process.Proceedings of the National Academy of Sciences of the United States of America · 2018
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Roberta MelchionnaTumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.
Pierluigi IapiccaTumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.
Francesca Di ModugnoTumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.
Paola TronoTumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.
Isabella SperdutiBiostatistics and Scientific Direction, Regina Elena National Cancer Institute , Rome, Italy.
Matteo FassanARC-NET Research Center, Department of Pathology and Diagnostics, University of Verona , Verona, Italy.
Ivana CataldoARC-NET Research Center, Department of Pathology and Diagnostics, University of Verona , Verona, Italy.
Borislav C RusevARC-NET Research Center, Department of Pathology and Diagnostics, University of Verona , Verona, Italy.
Rita T LawlorARC-NET Research Center, Department of Pathology and Diagnostics, University of Verona , Verona, Italy.
Maria Grazia DiodoroPathology Unit, Regina Elena National Cancer Institute , Rome, Italy.
Michele MilellaMedical Oncology, Regina Elena National Cancer Institute , Rome, Italy.
Gian Luca GraziHepato-pancreato-biliary Surgery Unit, Regina Elena National Cancer Institute , Rome, Italy.
Mina J BissellLawrence Berkeley National Laboratory, University of California , CA, USA.
Aldo ScarpaARC-NET Research Center, Department of Pathology and Diagnostics, University of Verona , Verona, Italy.
Paola NisticòTumour Immunology and Immunotherapy Unit, Regina Elena National Cancer Institute , Rome, Italy.
University of Verona · ITLawrence Berkeley National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease in need of prognostic markers to address therapeutic choices. We have previously shown that alternative splicing of the actin regulator, hMENA, generates hMENA

Indexed as

Actin CytoskeletonEMThMENA alternative splicingPDACTGF-β1

Identifiers

PMID28123868
PMCPMC5213039
OpenAlexW2513058809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.