Evidence map›Paper›PMID 28123843›Full record

ReviewAmerican journal of cancer research2017

Biological basis of cancer health disparities: resources and challenges for research.

Sachin K Deshmukh, Shafquat Azim, Aamir Ahmad, Haseeb Zubair, Nikhil Tyagi, Sanjeev K Srivastava, Arun Bhardwaj, Seema Singh, Rodney P Rocconi, Ajay P Singh

Open access · greenAbstract readReview
In one paragraph

Review in American journal of cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  17. Mitochondrion: I am more than a fuel server.Annals of translational medicine · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sachin K DeshmukhDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Shafquat AzimDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Aamir AhmadDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Haseeb ZubairDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Nikhil TyagiDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Sanjeev K SrivastavaDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South AlabamaMobile, Alabama 36604, USA; Division of Cell Biology and Genetics, Tatva Biosciences, Coastal Innovation Hub600 Clinic Drive, 3rd Floor, Mobile, Alabama 36688, USA.
Arun BhardwajDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Seema SinghDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South AlabamaMobile, Alabama 36604, USA; Department of Biochemistry and Molecular Biology, College of Medicine, University of South AlabamaMobile, Alabama 36688, USA.
Rodney P RocconiDepartment of Interdisciplinary Clinical Oncology, Mitchell Cancer Institute, University of South Alabama Mobile, Alabama 36604, USA.
Ajay P SinghDepartment of Oncologic Sciences, Mitchell Cancer Institute, University of South AlabamaMobile, Alabama 36604, USA; Department of Biochemistry and Molecular Biology, College of Medicine, University of South AlabamaMobile, Alabama 36688, USA.
USA Mitchell Cancer Institute · USUniversity of South Alabama · USSewanee: The University of the South · US

Funding

Molecular determinant of racial disparity in prostate cancerU01CA185490 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, AJAY PRATAP · 2014 to 2018
$1.7M
6 · The paper itself

Abstract

Last few decades have witnessed remarkable progress in our understanding of cancer initiation and progression leading to refinement of prevention and treatment approaches. Although these advances have improved the survival of cancer patients in general, certain racial/ethnic groups have benefited only partially. Footprints of cancer-associated racial disparities are very much evident in cancers of the prostate, breast, cervical, colorectal, endometrium, liver and lung. These health inequalities are mostly attributed to socioeconomic differences among races, but there is a growing realization that these may actually be due to inherent biological differences as well. Indeed, significant data now exist to support the biological basis of racial disparities in cancer, warranting basic research investigations, using appropriate tools and model systems. In this article, we have aimed to succinctly review the literature supporting the biological bases of racial disparities in cancer, along with available resources, databases and model systems that will be of interest to researchers. Moreover, we have highlighted the specific areas that need attention in terms of development of resources and/or tools, and discuss the opportunities and challenges in basic biological research in cancer health disparities.

Indexed as

biobankscell line modelPDXRacial disparityweb-based databanks

Identifiers

PMID28123843
PMCPMC5250676
OpenAlexW2583584486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.