ArticleLupus science & medicine2017
Predictors of peripheral arterial disease in SLE change with patient's age.
Article in Lupus science & medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Atherosclerosis features in rheumatic diseases - focus on peripheral artery disease.Frontiers in immunology · 2026Review
- Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Impaired ankle-brachial index in antiphospholipid syndrome: Beyond the traditional risk factors.Journal of clinical laboratory analysis · 2019Article
- L-sepiapterin restores SLE serum-induced markers of endothelial function in endothelial cells.Lupus science & medicine · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyse the differential influence of risk factors of peripheral artery disease (PAD) according to age in patients with SLE.
methods216 patients from the Lupus-Cruces cohort were divided in three age groups: ≤34 years, 35-49 years and ≥50 years. A low ankle-brachial index defined PAD. Significant variables were identified by univariant and multivariant analysis in each age group.
resultsDifferent factors were identified in different age groups: antiphospholipid antibodies/antiphospholipid syndrome and glucocorticoids in patients ≤34 years; in patients 35-49 years old, hypertension was the only statistically significant predictor, although a trend was observed for fibrinogen levels; a trend was observed for hypercholesterolaemia in those ≥50 years.
conclusionsAge may modulate the influence of risk factors for PAD in patients with SLE.
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