Evidence map›Paper›PMID 28123728›Full record

ArticleMolecular and clinical oncology2017

Clinicopathological features for predicting central and lateral lymph node metastasis in papillary thyroid microcarcinoma: Analysis of 66 cases that underwent central and lateral lymph node dissection.

Yang Tao, Chongjie Wang, Liye Li, Haijun Xing, Yun Bai, Bing Han, Zhiyan Liu, Xiangshan Yang, Shourong Zhu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  14. [Predictors for central lymph node metastases in papillary thyroid microcarcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yang TaoDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Chongjie WangDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Liye LiDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Haijun XingDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Yun BaiDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Bing HanDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Zhiyan LiuDepartment of Pathology, Qilu Hospital, Jinan, Shandong 250012, P.R. China.
Xiangshan YangDepartment of Pathology, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Shourong ZhuDepartment of Head and Neck, Affiliated Hospital of Shandong Medical Sciences, Jinan, Shandong 250031, P.R. China.
Affiliated Hospital of Shandong Academy of Medical Sciences · CNShandong First Medical University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently the surgical approach for papillary thyroid microcarcinoma (PTMC), particularly the range of lymph node dissection, remains controversial. The present study aims to evaluate the risk factors for central and lateral lymph node metastasis (CLNM and LLNM) for appropriate clinical decision of neck lymph node dissection in PTMC. A total of 66 cases of PTMC that underwent unilateral or bilateral lobectomy plus prophylactic cervical lymph node dissection were collected for clinicopathological evaluation, including age, gender, tumor size, subtypes, extrathyroidal invasion, multifocality, calcifications, loss of cellular polarity/cohesiveness (LOP/C) in the invasive front, CLNM and LLNM, and retrospectively analysis. Univariate analysis revealed that LOP/C was significantly associated with CLNM (P=0.001) and LLNM (P<0.0001). The male gender was a risk factor of CLNM (P=0.04), while the age <45 years, tumor size >0.5 cm and multifocality were high-risk factors of LLNM (P=0.022, 0.044 and 0.005, respectively). Multivariable analysis revealed that LOP/C was significantly associated with CLNM [P=0.007, odds ratio (OR)=7.765, 95% confidence interval (CI)=1.773-33.996] and LLNM [P=0.029, OR=5.717, 95% CI=1.190-27.470]. Both multivariable analysis and χ

Indexed as

central/lateral lymph node metastasisloss of cellular polarity/cohesivenesspapillary thyroid microcarcinomaprophylactic central lymph node dissectionprophylactic lateral lymph node dissection

Identifiers

PMID28123728
PMCPMC5244859
OpenAlexW2556307113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.