Evidence map›Paper›PMID 28123543›Full record

ArticleOncology letters2017

Increased chemosensitivity and radiosensitivity of human breast cancer cell lines treated with novel functionalized single-walled carbon nanotubes.

Yijun Jia, Ziyi Weng, Chuanying Wang, Mingjie Zhu, Yunshu Lu, Longlong Ding, Yongkun Wang, Xianhua Cheng, Qing Lin, Kejin Wu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

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  8. Application of Radiosensitizers in Cancer Radiotherapy.International journal of nanomedicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Yijun JiaDepartment of General Surgery, XinHua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China.
Ziyi WengDepartment of General Surgery, Shanghai International Medical Center, Shanghai 201318, P.R. China.
Chuanying WangSchool of Mechanical and Power Engineering, Shanghai Jiaotong University, Shanghai 200240, P.R. China.
Mingjie ZhuDepartment of Pathology, XinHua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China.
Yunshu LuDepartment of General Surgery, XinHua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China.
Longlong DingDepartment of General Surgery, XinHua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China.
Yongkun WangDepartment of Breast and Thyroid Surgery, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Xianhua ChengSchool of Mechanical and Power Engineering, Shanghai Jiaotong University, Shanghai 200240, P.R. China.
Qing LinDepartment of Radiology, Tenth People's Hospital, Shanghai Tongji University School of Medicine, Shanghai 200072, P.R. China.
Kejin WuDepartment of General Surgery, XinHua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China; Department of Breast Surgery, Shanghai Gynecology Hospital of Fudan University, Shanghai 200011, P.R. China.
XinHua Hospital · CNShanghai Jiao Tong University · CNLiaocheng People's Hospital · CNShanghai International Medical Center · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia is a major cause of treatment resistance in breast cancer. Single-walled carbon nanotubes (SWCNTs) exhibit unique properties that make them promising candidates for breast cancer treatment. In the present study, a new functionalized single-walled carbon nanotube carrying oxygen was synthesized; it was determined whether this material could increase chemosensitivity and radiosensitivity of human breast cancer cell lines, and the underlying mechanisms were investigated. MDA-MB-231 cells growing in folic acid (FA) free medium, MDA-MB-231 cells growing in medium containing FA and ZR-75-1 cells were treated with chemotherapy drugs or radiotherapy with or without tombarthite-modified-FA-chitosan (R-O

Indexed as

breast cancerchemotherapy sensitivityhypoxiaradiotherapy sensitivitysingle-walled carbon nanotubes

Identifiers

PMID28123543
PMCPMC5245142
OpenAlexW2552731891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.