Evidence map›Paper›PMID 28123540›Full record

ArticleOncology letters2017

Sometimes it is better to wait: First Italian case of a newborn with transient abnormal myelopoiesis and a favorable prognosis.

Guglielmo Salvatori, Silvia Foligno, Pietro Sirleto, Silvia Genovese, Serena Russo, Valentina Coletti, Andrea Dotta, Matteo Luciani

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guglielmo SalvatoriDepartment of Neonatology, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Silvia FolignoDepartment of Neonatology, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Pietro SirletoDepartment of Genetic Laboratories, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Silvia GenoveseDepartment of Genetic Laboratories, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Serena RussoDepartment of Genetic Laboratories, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Valentina ColettiDepartment of Hematology, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Andrea DottaDepartment of Neonatology, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Matteo LucianiDepartment of Hematology, Bambino Gesù Children's Hospital, I-00165 Rome, Italy.
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital leukemia is rare disease with an incidence of one to five cases per million births. Transient abnormal myelopoiesis (TAM), also called transient myeloproliferative disorder, is a pre-leukemia disorder that may occur in Down syndrome (DS) or non-DS infants. TAM may enter spontaneous remission; however, continual monitoring is required, as this disorder has been observed to develop into acute megakaryoblastic leukemia in 16-30% of cases. In the literature, 16 cases of TAM in non-DS infants have been reported. The case presented in the current study is, to the best of our knowledge, the first case of an Italian non-DS newborn presenting with clinical manifestations of acute leukemia at five days after birth, exhibiting a normal karyotype, trisomy 21 only in blast cells, and spontaneous remission. Chromosomal analyses on peripheral blood cells, bone marrow cells and dermal fibroblasts were conducted using a G-banding technique, and fluorescence

Indexed as

acute megakaryoblastic leukemiaDown syndrometransient abnormal myelopoiesistransient myeloproliferative disorder

Identifiers

PMID28123540
PMCPMC5244853
OpenAlexW2551826424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.