Evidence map›Paper›PMID 28123352›Full record

ArticleInternational journal of biological sciences2017

miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis.

Tao Wang, Jingjing Hou, Zengpeng Li, Zihan Zheng, Jie Wei, Dan Song, Tao Hu, Qiao Wu, James Y Yang, Jian-Chun Cai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tao WangDepartment of Gastrointestinal Surgery, Zhongshan Hospital affiliated to Xiamen University, Xiamen, China 361004.; Institute of Gastrointestinal Oncology, Medical college of Xiamen University, Xiang'an, Xiamen, China 361102.; Xiehe Clinical Medical College, Fujian Medical University, Fuzhou, China 350001.
Jingjing HouDepartment of Gastrointestinal Surgery, Zhongshan Hospital affiliated to Xiamen University, Xiamen, China 361004.; Institute of Gastrointestinal Oncology, Medical college of Xiamen University, Xiang'an, Xiamen, China 361102.; Xiehe Clinical Medical College, Fujian Medical University, Fuzhou, China 350001.
Zengpeng LiState Key Laboratory Breeding Base of Marine Genetic Resources, Third Institute of Oceanography, State Oceanic Administration, 184 University Road, Xiamen, China 361005.
Zihan ZhengCollege of Arts and Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514.
Jie WeiDepartment of Basic Medical Sciences of Medical College, Xiamen University, Xiang'an, Xiamen, China 361102.
Dan SongState Key Laboratory of Cellular Stress Biology and Department of Biomedical Sciences, School of Life Sciences, Xiamen University, Xiang'an, Xiamen, China 361102.
Tao HuDepartment of Basic Medical Sciences of Medical College, Xiamen University, Xiang'an, Xiamen, China 361102.
Qiao WuState Key Laboratory of Cellular Stress Biology and Department of Biomedical Sciences, School of Life Sciences, Xiamen University, Xiang'an, Xiamen, China 361102.
James Y YangState Key Laboratory of Cellular Stress Biology and Department of Biomedical Sciences, School of Life Sciences, Xiamen University, Xiang'an, Xiamen, China 361102.
Jian-Chun CaiDepartment of Gastrointestinal Surgery, Zhongshan Hospital affiliated to Xiamen University, Xiamen, China 361004.; Institute of Gastrointestinal Oncology, Medical college of Xiamen University, Xiang'an, Xiamen, China 361102.; Xiehe Clinical Medical College, Fujian Medical University, Fuzhou, China 350001.
Zhongshan Hospital of Xiamen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs are a novel class of gene regulators that function as oncogenes or tumor suppressors. In our current study, we investigated the role of miR-15a-3p and miR-16-1-3p in the regulation of

Indexed as

AnimalsCell Line, TumorCell MovementGene Expression Regulation, NeoplasticHumansMiceMice, NudeMicroRNAsNeoplasm InvasivenessStomach NeoplasmsTwist-Related Protein 1MicroRNAsMirn15a microRNA, mouseMIRN15 microRNA, humanMIRN16 microRNA, humanMirn16 microRNA, mouseTwist-Related Protein 1cell invasion and metastasis.Gastric cancermiR-15a-3pmiR-16-1-3pTwist1

Identifiers

PMID28123352
PMCPMC5264267
OpenAlexW2578789454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.