Evidence map›Paper›PMID 28123322›Full record

ArticleJournal of ginseng research2017

The effect of Korean Red Ginseng extract on rosiglitazone-induced improvement of glucose regulation in diet-induced obese mice.

Mi-Jeong Oh, Hyun-Ju Kim, Eun-Young Park, Na-Hee Ha, Mun-Gyu Song, Sang-Hyun Choi, Boe-Gwun Chun, Dong-Hoon Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mi-Jeong OhDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Hyun-Ju KimDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Eun-Young ParkDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Na-Hee HaDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Mun-Gyu SongDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Sang-Hyun ChoiDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Boe-Gwun ChunDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Dong-Hoon KimDepartment of Pharmacology, Korea University College of Medicine, Seoul, Korea.
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKorean Red Ginseng extract (KRG,

methodsOral glucose tolerance tests (oGTTs) were performed after 4 days of treatment with a vehicle (CON), KRG [500 mg/kg body weight (b.w.)], ROSI (3.75 mg/kg b.w, 7.5 mg/kg b.w, and 15 mg/kg b.w.), or ROSI and KRG (RK) in obese mice on a high-fat diet. Adipose tissue morphology, crown-like structures (CLSs), and inflammation were compared by hematoxylin-eosin staining or quantitative reverse transcription polymerase chain reaction.

resultsThe area under the glucose curve (AUC) was significantly lower in the RK group (15 mg/kg b.w. and 500 mg/kg b.w. for ROSI and KRG, respectively) than in the CON group. There was no significant difference in the AUC between the CON and the other groups. Furthermore, the AUC was significantly lower in the RK group than in the ROSI group. The expression of the

conclusionOur results show a potential enhancement of ROSI-induced improvement of glucose regulation by the combined treatment with KRG.

Indexed as

adipose tissueglucose regulationinflammationKorean Red Ginsengrosiglitazone

Identifiers

PMID28123322
PMCPMC5223077
OpenAlexW2228516352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.