Vps13 and Cdc31/centrin: Puzzling partners in membrane traffic.

Open access · hybridAbstract readComment

In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

0.5field-weighted citation impact, top 39% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

VPS13 has an important role in female germline development in Arabidopsis.The Plant journal : for cell and molecular biology · 2026
Article
Structural Basis for the Functional Diversity of Centrins: A Focus on Calcium Sensing Properties and Target Recognition.International journal of molecular sciences · 2021
Review
The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization.PLoS genetics · 2020
Article
Identification of two compound heterozygous VPS13A large deletions in chorea-acanthocytosis only by protein and quantitative DNA analysis.Molecular genetics & genomic medicine · 2020
Article
Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects.Annals of neurology · 2018
Article

4 · The record

Corrections and comments

Comment on
The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.2017

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Margaret D MyersDepartment of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.

Gregory S PayneDepartment of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095 gpayne@mednet.ucla.edu.ORCID 0000-0002-5267-5443

University of California, Los Angeles · US

Funding

MOLECULAR STUDIES OF SELECTIVE PROTEIN TRANSPORTR01GM039040 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PAYNE, GREGORY S · 1988 to 2016

$6.4M

NIGMS NIH HHS R01 GM039040

6 · The paper itself

Abstract

Yeast Vps13 is a member of a conserved protein family that includes human homologues associated with neurodegenerative and developmental disorders. In this issue, De et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606078) establish direct roles for Vps13 and its surprising binding partner, the calcium-binding centrin Cdc31, in trans-Golgi network (TGN) to endosome traffic and TGN homotypic fusion.

Indexed as

Calcium-Binding Proteinstrans-Golgi NetworkHumansProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCalcium-Binding ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID28122956

DOI10.1083/jcb.201612026

PMCPMC5294792

OpenAlexW2581817071

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-SA

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.