Evidence map›Paper›PMID 28122820›Full record

ArticleMolecular biology of the cell2017

Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage

Wiebke Petersen, Werner Stenzel, Olivier Silvie, Judith Blanz, Paul Saftig, Kai Matuschewski, Alyssa Ingmundson

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Frontiers in immunology · 2025
    Article
  6. Article
  7. Review
  8. Understanding theFrontiers in parasitology · 2024
    Review
  9. Frontiers in veterinary science · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. iScience · 2022
    Article
  15. The role of cholesterol in invasion and growth of malaria parasites.Frontiers in cellular and infection microbiology · 2022
    Review
  16. Novel Insights Into Sterol Uptake and Intracellular Cholesterol Trafficking DuringFrontiers in cellular and infection microbiology · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Wiebke PetersenMolecular Parasitology, Humboldt University, 10115 Berlin, Germany.
Werner StenzelInstitute for Neuropathology, Charité-Universitätsmedizin, 10117 Berlin, Germany.
Olivier SilvieInstitut National de la Santé et de la Recherche Médicale, U1135, Centre d'Immunologie et des Maladies Infectieuses, F-75013 Paris, France.
Judith BlanzInstitute of Biochemistry, Christian-Albrechts-University of Kiel, 24098 Kiel, Germany.
Paul SaftigInstitute of Biochemistry, Christian-Albrechts-University of Kiel, 24098 Kiel, Germany.
Kai MatuschewskiMolecular Parasitology, Humboldt University, 10115 Berlin, Germany.
Alyssa IngmundsonMolecular Parasitology, Humboldt University, 10115 Berlin, Germany alyssa.ingmundson@hu-berlin.de.
Humboldt-Universität zu Berlin · DEChristian-Albrechts-Universität zu Kiel · DECharité - Universitätsmedizin Berlin · DEInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While lysosomes are degradative compartments and one of the defenses against invading pathogens, they are also hubs of metabolic activity. Late endocytic compartments accumulate around

Indexed as

AndrostenesAnimalsCholesterolEndosomesLiverLysosomal-Associated Membrane Protein 1Lysosomal-Associated Membrane Protein 2Lysosomal Membrane ProteinsLysosomesMembrane ProteinsNiemann-Pick Disease, Type CParasitesPlasmodium berghei3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-oneAndrostenesCholesterolLysosomal-Associated Membrane Protein 1Lysosomal-Associated Membrane Protein 2Lysosomal Membrane ProteinsMembrane Proteins

Identifiers

PMID28122820
PMCPMC5349780
OpenAlexW2581879485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.