Evidence map›Paper›PMID 28122655›Full record

ArticleEpidemiology and psychiatric sciences2018

A comparative study of psychotic and affective symptoms in Rwandan and Kenyan students.

A Owoso, S Jansen, D M Ndetei, A Musau, V N Mutiso, C Mudenge, A Ngirababyeyi, A Gasovya, D Mamah

Open access · hybridAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

A OwosoDepartment of Psychiatry,Washington University School of Medicine,St. Louis, MO,USA.
S JansenCenter for Mental Health,University of Rwanda College of Medicine and Health Sciences,Kigali,Rwanda.
D M NdeteiAfrica Mental Health Foundation,Nairobi,Kenya.
A MusauAfrica Mental Health Foundation,Nairobi,Kenya.
V N MutisoAfrica Mental Health Foundation,Nairobi,Kenya.
C MudengeUniversity Teaching Hospital of Butare,Rwanda.
A NgirababyeyiCenter for Mental Health,University of Rwanda College of Medicine and Health Sciences,Kigali,Rwanda.
A GasovyaCenter for Mental Health,University of Rwanda College of Medicine and Health Sciences,Kigali,Rwanda.
D MamahDepartment of Psychiatry,Washington University School of Medicine,St. Louis, MO,USA.
University of Rwanda · RWAfrica Mental Health Foundation · KEWashington University in St. Louis · USUniversity of Nairobi · KEUniversity Teaching Hospital of Butare · RW

Funding

Genes, Behavior and Psychosis Risk in KenyaR56MH111300 · NIMH · WASHINGTON UNIVERSITY · PI MAMAH, DANIEL · 2016 to 2016
$640k
IDENTIFICATION OF PSYCHOSIS-RISK TRAITS IN AFRICAR21MH095645 · NIMH · WASHINGTON UNIVERSITY · PI MAMAH, DANIEL · 2013 to 2014
$270k
NIMH NIH HHS R21 MH095645NIMH NIH HHS R56 MH111300
6 · The paper itself

Abstract

aimsWar and conflict are known to adversely affect mental health, although their effects on risk symptoms for psychosis development in youth in various parts of the world are unclear. The Rwandan genocide of 1994 and Civil War had widespread effects on the population. Despite this, there has been no significant research on psychosis risk in Rwanda. Our goal in the present study was to investigate the potential effects of genocide and war in two ways: by comparing Rwandan youth born before and after the genocide; and by comparing Rwandan and Kenyan adolescents of similar age.

methodsA total of 2255 Rwandan students and 2800 Kenyan students were administered the Washington Early Recognition Center Affectivity and Psychosis (WERCAP) Screen. Prevalence, frequency and functional impairment related to affective and psychosis-risk symptoms were compared across groups using univariate and multivariate statistics.

resultsRwandan students born before the end of the genocide and war in 1994 experienced higher psychotic and affective symptom load (p's < 0.001) with more functional impairment compared with younger Rwandans. 5.35% of older Rwandan students met threshold for clinical high-risk of psychosis by the WERCAP Screen compared with 3.19% of younger Rwandans (χ 2 = 5.36; p = 0.02). Symptom severity comparisons showed significant (p < 0.001) group effects between Rwandan and Kenyan secondary school students on affective and psychotic symptom domains with Rwandans having higher symptom burden compared with Kenyans. Rwandan female students also had higher rates of psychotic symptoms compared with their male counterparts - a unique finding not observed in the Kenyan sample.

conclusionsThese results suggest extreme conflict and disruption to country from genocide and war can influence the presence and severity of psychopathology in youth decades after initial traumatic events.

Indexed as

AdolescentAffective SymptomsFemaleGenocideHumansKenyaMental HealthPrevalencePsychotic DisordersRwandaStudentsYoung AdultadolescentsAfricahigh-riskwarWERCAP

Identifiers

PMID28122655
PMCPMC6998958
OpenAlexW2580684664

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.