Evidence map›Paper›PMID 28122534›Full record

ArticleBMC cancer2017

An increase in physical activity after colorectal cancer surgery is associated with improved recovery of physical functioning: a prospective cohort study.

Moniek van Zutphen, Renate M Winkels, Fränzel J B van Duijnhoven, Suzanne A van Harten-Gerritsen, Dieuwertje E G Kok, Peter van Duijvendijk, Henk K van Halteren, Bibi M E Hansson, Flip M Kruyt, Ernst J Spillenaar Bilgen and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Effect of home-based exercise prehabilitation on postoperative outcomes in colorectal cancer surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  6. Lifestyle perceptions following multimodal prehabilitation in patients undergoing cancer surgery: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Moniek van ZutphenDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands.ORCID 0000-0002-2368-0606
Renate M WinkelsDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands. renate.winkels@wur.nl.
Fränzel J B van DuijnhovenDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands.
Suzanne A van Harten-GerritsenDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands.
Dieuwertje E G KokDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands.
Peter van DuijvendijkDepartment of surgery, Gelre Hospital, Apeldoorn, The Netherlands.
Henk K van HalterenDepartment of Internal Medicine, Admiraal de Ruyter Hospital, Goes/Vlissingen, The Netherlands.
Bibi M E HanssonDepartment of Surgery, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Flip M KruytDepartment of Surgery, Gelderse Vallei Hospital, Ede, The Netherlands.
Ernst J Spillenaar BilgenDepartment of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
Johannes H W de WiltDepartment of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Jaap J DronkersDepartment of Physical Therapy, Gelderse Vallei Hospital, Ede, The Netherlands.
Ellen KampmanDivision of Human Nutrition, Wageningen University & Research, P.O Box 17, 6700 AA, Wageningen, The Netherlands.
Wageningen University & Research · NLZiekenhuis Gelderse Vallei · NLAdmiraal De Ruyter Ziekenhuis · NLCanisius-Wilhelmina Ziekenhuis · NLGelre Hospitals · NLRadboud University Nijmegen · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe influence of physical activity on patient-reported recovery of physical functioning after colorectal cancer (CRC) surgery is unknown. Therefore, we studied recovery of physical functioning after hospital discharge by (a) a relative increase in physical activity level and (b) absolute activity levels before and after surgery.

methodsWe included 327 incident CRC patients (stages I-III) from a prospective observational study. Patients completed questionnaires that assessed physical functioning and moderate-to-vigorous physical activity shortly after diagnosis and 6 months later. Cox regression models were used to calculate prevalence ratios (PRs) of no recovery of physical functioning. All PRs were adjusted for age, sex, physical functioning before surgery, stage of disease, ostomy and body mass index.

resultsAt 6 months post-diagnosis 54% of CRC patients had not recovered to pre-operative physical functioning. Patients who increased their activity by at least 60 min/week were 43% more likely to recover physical function (adjusted PR 0.57 95%CI 0.39-0.82), compared with those with stable activity levels. Higher post-surgery levels of physical activity were also positively associated with recovery (P for trend = 0.01). In contrast, activity level before surgery was not associated with recovery (P for trend = 0.24).

conclusionsAt 6 month post-diagnosis, about half of CRC patients had not recovered to preoperative functioning. An increase in moderate-to-vigorous physical activity after CRC surgery was associated with enhanced recovery of physical functioning. This benefit was seen regardless of physical activity level before surgery. These associations provide evidence to further explore connections between physical activity and recovery from CRC surgery after discharge from the hospital.

Indexed as

ExerciseAgedColorectal NeoplasmsColorectal SurgeryFemaleHumansMaleMiddle AgedQuality of LifeRisk FactorsSurveys and QuestionnairesColorectal cancerColorectal surgeryEpidemiologyPhysical activityRecovery of functionRehabilitation

Identifiers

PMID28122534
PMCPMC5264442
OpenAlexW2581545932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.