Evidence map›Paper›PMID 28122513›Full record

ArticleBMC infectious diseases2017

Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China.

Kaisen Chen, Yanfang Huang, Qiuyue Song, Chenhui Wu, Xiaowen Chen, Lingbing Zeng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular Epidemiology ofInfection and drug resistance · 2023
    Article
  4. Severe problem of macrolides resistance to common pathogens in China.Frontiers in cellular and infection microbiology · 2023
    Review
  5. Article
  6. Inhibition of Drug Resistance ofPolish journal of microbiology · 2019
    Article
  7. Antibiotics (Basel, Switzerland) · 2019
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaisen ChenDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, 17 Yongwaizhengjie, Nanchang, 330006, China. chenks100@126.com.
Yanfang HuangDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, 17 Yongwaizhengjie, Nanchang, 330006, China.
Qiuyue SongThe College of Public Health of Nanchang University, Nanchang, 330006, China.
Chenhui WuThe College of Public Health of Nanchang University, Nanchang, 330006, China.
Xiaowen ChenDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, 17 Yongwaizhengjie, Nanchang, 330006, China.
Lingbing ZengDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, 17 Yongwaizhengjie, Nanchang, 330006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo understand the relationship between the Staphylococcus aureus infection rate and the reasonable usage of antibiotics, which will help in the effective control of MRSA infection.

methodsAll data were obtained by the application of the nosocomial infection surveillance network. Drug resistance, departmental sources, and isolated sites as well as infection rate variations of S. aureus were analyzed in the 7-year period in key departments.

resultsBetween 2008 and 2014, 2525 strains of S. aureus isolates, mainly from sputum, skin/soft tissue, bloodstreams were collected from several hospital departments including respiratory, burn, brain surgery, orthopedics, ICU, and emergency. During these periods, the resistance rate of S. aureus to most drugs, including oxacillin, tetracycline, erythromycin, clindamycin, gentamicin, and ciprofloxacin, showed a tendency to decrease. The resistance to sulphamethoxazole/trimethoprim showed the opposite trend (P = 0.075) and there were no S. aureus strains resistant to linezolid and vancomycin. The MRSA infection rate was different across crucial hospital departments, with the burns department and ICU maintaining a high infection level. Over the 7-year period, both the brain surgery and the emergency departments had an expected upward trend (P < 0.05), while the orthopedic department showed a clear downward trend (P < 0.05) in MRSA infection rate.

conclusionHospitals should continue to maintain the current pattern of antibiotic administration, while more effective measures should be taken to reduce the high MRSA infection rate in some important hospital departments.

Indexed as

Staphylococcal InfectionsAnti-Bacterial AgentsChinaClindamycinCross InfectionDrug Resistance, Multiple, BacterialErythromycinHospitals, TeachingHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsStaphylococcus aureusTertiary Care CentersTetracyclineAnti-Bacterial AgentsClindamycinErythromycinTetracyclineChinaDrug resistanceS. aureusTrend

Identifiers

PMID28122513
PMCPMC5267434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.