ArticleBMC neuroscience2017
Evoked potentials and behavioral performance during different states of brain arousal.
Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Mental Fatigue-Associated Decrease in Table Tennis Performance: Is There an Electrophysiological Signature?International journal of environmental research and public health · 2021Trial
- Preattentive and Predictive Processing of Visual Motion.Scientific reports · 2018Trial
- The impact of emotional dysregulation and comorbid depressive symptoms on clinical features, brain arousal, and treatment response in adults with ADHD.Frontiers in psychiatry · 2023Article
- Effect of Acoustic fMRI-Scanner Noise on the Human Resting State.Brain topography · 2023Article
- Methodology and preliminary data on feasibility of a neurofeedback protocol to improve visual attention to letters in mild Alzheimer's disease.Contemporary clinical trials communications · 2022Article
- EEG as a translational biomarker and outcome measure in fragile X syndrome.Translational psychiatry · 2022Review
- Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation.Scientific data · 2021Article
- The Big Five Personality Traits and Brain Arousal in the Resting State.Brain sciences · 2021Article
- Is brain arousal regulation a predictor of response to psychostimulant therapy in adult ADHD patients?European archives of psychiatry and clinical neuroscience · 2020Article
- Fatigue in Cancer and Neuroinflammatory and Autoimmune Disease: CNS Arousal Matters.Brain sciences · 2020Article
- Vulnerability to bipolar disorder is linked to sleep and sleepiness.Translational psychiatry · 2019Article
- Human brain arousal in the resting state: a genome-wide association study.Molecular psychiatry · 2019Article
- Brain arousal regulation and depressive symptomatology in adults with attention-deficit/hyperactivity disorder (ADHD).BMC neuroscience · 2019Article
- Changes in Event-Related Potentials Underlying Coma Recovery in Patients with Large Left Hemispheric Infarction.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Impact of brain arousal and time-on-task on autonomic nervous system activity in the wake-sleep transition.BMC neuroscience · 2018Article
- Coupling and dynamics of cortical and autonomic signals are linked to central inhibition during the wake-sleep transition.Scientific reports · 2017Article
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7 authors.
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Abstract
backgroundPrevious studies compared evoked potentials (EPs) between several sleep stages but only one uniform wake state. However, using electroencephalography (EEG), several arousal states can be distinguished before sleep onset. Recently, the Vigilance Algorithm Leipzig (VIGALL 2.0) has been developed, which automatically attributes one out of seven EEG-vigilance stages to each 1-s EEG segment, ranging from stage 0 (associated with cognitively active wakefulness), to stages A1, A2 and A3 (associated with relaxed wakefulness), to stages B1 and B2/3 (associated with drowsiness) up to stage C (indicating sleep onset). Applying VIGALL, we specified the effects of these finely differentiated EEG-vigilance stages (indicating arousal states) on EPs (P1, N1, P2, N300, MMN and P3) and behavioral performance. Subjects underwent an ignored and attended condition of a 2-h eyes-closed oddball-task. Final analysis included 43 subjects in the ignored and 51 subjects in the attended condition. First, the effect of brain arousal states on EPs and performance parameters were analyzed between EEG-vigilance stages A (i.e. A1, A2 and A3 combined), B1 and B2/3&C (i.e. B2/3 and C combined). Then, in a second step, the effects of the finely differentiated EEG-vigilance stages were further specified.
resultsComparing stages A versus B1 versus B2/3&C, a significant effect of EEG-vigilance stages on all behavioral parameters and all EPs, with exception of MMN and P3, was found. By applying VIGALL, a more detailed view of arousal effects on EP and performance was possible, such as the finding that the P2 showed no further significant increase in stages deeper than B1. Stage 0 did not differ from any of the A-stages. Within more fine-graded stages, such as the A-substages, EPs and performance only partially differed. However, these analyses were partly based on small sample sizes and future studies should take effort to get enough epochs of rare stages (such as A3 and C).
conclusionsA clear impact of arousal on EPs and behavioral performance was obtained, which emphasize the necessity to consider arousal effects when interpreting EPs.
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