ArticleJournal of clinical and experimental neuropsychology2017
Screening for neurocognitive impairment in HIV-positive adults aged 50 years and older: Montreal Cognitive Assessment relates to self-reported and clinician-rated everyday functioning.
Article in Journal of clinical and experimental neuropsychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Montreal Cognitive Assessment (MoCA) for HIV-Associated Neurocognitive Disorders.Neuropsychology review · 2019Pooled it
- Assessing cognitive impairment in HIV-infected: a comparative study of international HIV Dementia Scale, HIV Dementia Scale Italian version and Montreal cognitive assessment in clinical practice.Journal of neurovirology · 2025Article
- Neurocognitive Impairment and HIV Treatment Engagement in Men Who Have Sex With Men Living With HIV Who Report Chronic Pain and Substance Use.AIDS research and treatment · 2025Article
- Health Literacy Mediates Racial Differences in Cognitive Functioning among African American/Black and White People with and without HIV in the Deep South.Nursing (Auckland, N.Z.) · 2025Article
- Moderate-to-severe cognitive impairment is associated with both recent and chronic alcohol misuse in people with HIV: The New Orleans alcohol use in HIV (NOAH) study.Alcohol, clinical & experimental research · 2024Article
- Frailty and Aging in HIV- Status Post 13 Years of National Awareness.The Journal of frailty & aging · 2023Review
- Neurocognitive performance and quality of life of older adults with HIV on antiretroviral treatment in Northern Thailand.Journal of the International AIDS Society · 2022Article
- Factors associated to neurocognitive impairment in older adults living with HIV.European journal of medical research · 2022Article
- Self-Reported Cognitive Function in Persons with Nonneurological Chronic Diseases: A Systematic Review.Journal of aging research · 2022Review
- International HIV Dementia Scale for HIV-Associated Neurocognitive Disorders: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2021Review
- Robot-Based Assessment of HIV-Related Motor and Cognitive Impairment for Neurorehabilitation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021Article
- HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research.Psychiatry research · 2020Article
- Robot-based assessment of HIV-related motor and cognitive impairment for neurorehabilitation.medRxiv : the preprint server for health sciences · 2020Article
- Article
- An Exploratory Study of Correlates of Allostatic Load in Older People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Functional deficits and other psychiatric associations with abnormal scores on the Montreal Cognitive Assessment (MoCA) in older HIV-infected patients.International psychogeriatrics · 2020Article
- Observational
- Resilience attenuates the association between neurocognitive functioning and everyday functioning in individuals aging with HIV in the Deep South.International journal of geriatric psychiatry · 2019Article
- Cerebral Vasoreactivity Evaluated by the Breath-Holding Challenge Correlates With Performance on a Cognitive Screening Test in Persons Living With Treated HIV Infection in China.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Examining the effectiveness of a cognitive intervention to improve cognitive function in a population of older adults living with HIV: a pilot study.Therapeutic advances in infectious disease · 2018Article
Corrections and comments
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Authors and funding
6 authors.
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Abstract
As the HIV+ population ages, the risk for and need to screen for HIV-associated neurocognitive disorders (HAND) increases. The aim of this study is to determine the utility and ecological validity of the Montreal Cognitive Assessment (MoCA) among older HIV+ adults. A total of 100 HIV+ older adults aged 50 years or over completed a comprehensive neuromedical and neurocognitive battery, including the MoCA and several everyday functioning measures. The receiver operating characteristic curve indicates ≤26 as the optimal cut-off balancing sensitivity (84.2%) and specificity (55.8%) compared to "gold standard" impairment as measured on a comprehensive neuropsychological battery. Higher MoCA total scores are significantly (p < .01) associated with better performance in all individual cognitive domains except motor abilities, with the strongest association with executive functions (r = -0.49, p < .01). Higher MoCA total scores are also significantly (p <.01) associated with fewer instrumental activities of daily living declines (r = -0.28), fewer everyday cognitive symptoms (r = -0.25), and better clinician-rated functional status (i.e., Karnofsky scores; r = 0.28); these associations remain when controlling for depressive symptoms. HIV+ individuals who are neurocognitively normal demonstrate medium-to-large effect size differences in their MoCA performance compared to those with asymptomatic neurocognitive impairment (d = 0.85) or syndromic HAND (mild neurocognitive disorder or HIV-associated dementia; d = 0.78), while the latter two categories do not differ. Although limited by less than optimal specificity, the MoCA demonstrates good sensitivity and ecological validity, which lends support to its psychometric integrity as a brief cognitive screening tool among older HIV+ adults.
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