Evidence map›Paper›PMID 28122194›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2017

Histochemical Examination on Periodontal Tissues of Klotho-Deficient Mice Fed With Phosphate-Insufficient Diet.

Kumiko Hikone, Tomoka Hasegawa, Erika Tsuchiya, Hiromi Hongo, Muneteru Sasaki, Tomomaya Yamamoto, Ai Kudo, Kimimitsu Oda, Mai Haraguchi, Paulo Henrique Luiz de Freitas and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Klotho in OsxSignal transduction and targeted therapy · 2022
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Kumiko HikoneDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Tomoka HasegawaDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Erika TsuchiyaDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Hiromi HongoDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Muneteru SasakiDepartment of Applied Prosthodontics, Unit of Translational Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan (MS).
Tomomaya YamamotoDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Ai KudoDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Kimimitsu OdaDivision of Biochemistry, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan (KO).
Mai HaraguchiDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Paulo Henrique Luiz de FreitasDepartment of Oral and Maxillofacial Surgery, Dr. Mário Gatti Municipal Hospital, Campinas, Brazil (PHLF).
Minqi LiShandong Provincial Key Laboratory of Oral Biomedicine, School of Stomatology, Shandong University, Jinan, China (ML).
Junichiro IidaDepartment of Orthodontics (KH, JI), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Norio AmizukaDepartment of Developmental Biology of Hard Tissue (KH, TH, ET, HH, TY, AK, MH, NA), Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Nagasaki University · JPHokkaido University · JPHospital Estadual Mário Covas · BRNiigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To elucidate which of elevated serum concentration of inorganic phosphate (Pi) or disrupted signaling linked to αklotho/fibroblast growth factor 23 (FGF23) is a predominant regulator for senescence-related degeneration seen in αKlotho-deficient mice, we have examined histological alteration of the periodontal tissues in the mandibular interalveolar septum of αKlotho-deficient mice fed with Pi-insufficient diet. We prepared six groups of mice: wild-type, kl/kl, and αKlotho

Indexed as

AnimalsDietFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseHistocytochemistryKlotho ProteinsMaleMandibleMiceMice, Mutant StrainsMutation, MissensePeriodontal LigamentPeriodontiumPhosphatesFgf23 protein, mouseFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseKlotho ProteinsPhosphatesDMP-1osteopontinperiodontal tissuephosphateαKlotho-deficient mice

Identifiers

PMID28122194
PMCPMC5407563
OpenAlexW2582484725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.