Evidence map›Paper›PMID 28122175›Full record

ArticleInfluenza and other respiratory viruses2017

Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011.

Orienka Hellferscee, Florette K Treurnicht, Stefano Tempia, Ebrahim Variava, Halima Dawood, Kathleen Kahn, Adam L Cohen, Marthi Pretorius, Cheryl Cohen, Shabir A Madhi and 1 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Orienka HellfersceeNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.ORCID 0000-0001-9246-8927
Florette K TreurnichtNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Stefano TempiaNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Ebrahim VariavaUniversity of the Witwatersrand, Johannesburg, South Africa.
Halima DawoodPietermaritzburg Metropolitan Hospital, Pietermaritzburg, South Africa.
Kathleen KahnUniversity of the Witwatersrand, Johannesburg, South Africa.
Adam L CohenCentres for Disease Control and Prevention, Atlanta, Georgia, USA.
Marthi PretoriusUniversity of Pretoria, Pretoria, South Africa.
Cheryl CohenNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Shabir A MadhiNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Marietjie VenterCentres for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09U01IP001048 · IP · NATIONAL HEALTH LABORATORY SERVICE · PI COHEN, CHERYL · 2016 to 2020
$19.9M
NCIRD CDC HHS U01 IP001048NCIRD CDC HHS U51 IP000155
6 · The paper itself

Abstract

backgroundHuman enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa.

objectivesWe aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009-2011. PATIENTS/

methodsStudy samples from patients were tested for the presence of enterovirus using a polymerase chain reaction assay.

results8.2% (842/10 260) of SARI cases tested positive for enterovirus; 16% (7/45) were species EV-A, 44% (20/45) EV-B, 18% (8/45) EV-C and 22% (10/45) EV-D. Seventeen different EV serotypes were identified within EV-A to EV-D, of which EV-D68 (22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent.

conclusionsEV-D68 should be monitored in South Africa to assess the emergence of highly pathogenic strains.

Indexed as

AdolescentChildChild, PreschoolEnterovirusEnterovirus D, HumanEnterovirus InfectionsFemaleHumansInfantMalePhylogenyRespiratory Tract InfectionsSerogroupSouth AfricaenterovirusEV-D68pneumoniaSouth Africa

Identifiers

PMID28122175
PMCPMC5410726

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.