Evidence map›Paper›PMID 28122002›Full record

ArticlePloS one2017

A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

Ted Melcer, Jay Walker, Vibha Bhatnagar, Erin Richard, V Franklin Sechriest, Michael Galarneau

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Overview of the limb injury measurement battery for quality of life (LIMB-QOL).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
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  6. Bone Health Deterioration in Transfemoral Prosthetic Users: An Analytical Biomechanical Explanation.International journal for numerical methods in biomedical engineering · 2025
    Article
  7. Combat amputee care for Global War on Terror Veterans: A systematic review.Journal of military, veteran and family health · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ted MelcerDepartment of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, California, United States of America.ORCID http://orcid.org/0000-0001-8330-6985
Jay WalkerDepartment of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, California, United States of America.
Vibha BhatnagarDepartment of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, California, United States of America.
Erin RichardDepartment of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, California, United States of America.
V Franklin SechriestVA Minneapolis Healthcare System, Minneapolis, Minnesota, United States of America.
Michael GalarneauDepartment of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, California, United States of America.
Naval Health Research Center · USUniversity of California San Diego · USMinneapolis VA Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107). Patient medical records were analyzed for four years postinjury. After adjusting for group differences, early amputation was generally associated with a lower or similar prevalence for adverse physical and psychological diagnoses (e.g., pain, osteoarthritis, posttraumatic stress disorder) versus late amputation and/or limb salvage. By contrast, early amputation was associated with an increased likelihood of osteoporosis during the first year postinjury. The prevalence of posttraumatic stress disorder increased for all patient groups over four years postinjury, particularly in the second year. The different clinical outcomes among combat extremity injured patients treated with early amputation, late amputation, or limb salvage highlight their different healthcare requirements. These findings can inform and optimize the specific treatment pathways that address the physical and psychological healthcare needs of such patients over time.

Indexed as

Recovery of FunctionAdultAmputation, SurgicalHumansInjury Severity ScoreLeg InjuriesMaleOsteoporosisPostoperative ComplicationsPrevalencePrognosisStress Disorders, Post-TraumaticSurgical Wound InfectionTime FactorsUnited StatesYoung Adult

Identifiers

PMID28122002
PMCPMC5266314
OpenAlexW2581736124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.