ReviewAIDS (London, England)2017
Patient-reported barriers and facilitators to antiretroviral adherence in sub-Saharan Africa.
Review in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
106 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Impact of Financial Incentives on Intimate Partner Violence for Women Living with HIV Initiating Antiretroviral Therapy.AIDS and behavior · 2025Trial
- Including the Household: Individual, Community and Household Factors Affecting Antiretroviral Therapy Adherence After ART Initiation in Cape Town, South Africa.AIDS and behavior · 2024Trial
- Early HIV viral suppression associated with subsequent 12-month treatment success among people living with HIV in South Africa.HIV medicine · 2024Trial
- Reducing HIV-Associated Post-Hospital Mortality Through Home-Based Care in South Africa: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Trial
- Impact of Community Support Workers in Rural Ethiopia on Emotional and Psychosocial Health of Persons Living with HIV: Results of a Three-Year Randomized Community Trial.AIDS and behavior · 2023Trial
- Changing contextual factors from baseline to 9-months post-HIV diagnosis predict 5-year mortality in Durban, South Africa.AIDS care · 2021Trial
- SEARCH Human Immunodeficiency Virus (HIV) Streamlined Treatment Intervention Reduces Mortality at a Population Level in Men With Low CD4 Counts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Trial
- Two-way mobile phone intervention compared with standard-of-care adherence support after second-line antiretroviral therapy failure: a multinational, randomised controlled trial.The Lancet. Digital health · 2019Trial
- A Scoping Review Assessing the Relationship Between Structural, Functional, and Perceived Social Support with Antiretroviral Therapy (ART) in the Last Decade.AIDS and behavior · 2026Article
- Patterns of Workplace Absenteeism Across Levels of Virological Failure Among Employed Adults Co-Infected with HIV and Pulmonary Tuberculosis in the Govan Mbeki Sub-District, South Africa: A Retrospective Record Review.Healthcare (Basel, Switzerland) · 2026Article
- The Mental Health of Adults Living with HIV in Sub-Saharan Africa: Interventions along the HIV Care Continuum - A Systematic Review.AIDS and behavior · 2026Review
- Navigating the HIV continuum of care from treatment to retention strategies in Carnot, Central African Republic: a sequential explanatory mixed-methods study.BMJ global health · 2026Article
- Quantifying the impact of health service delivery barriers on access to healthcare: a case study of antiretroviral therapy in Mali.BMJ global health · 2026Article
- Article
- Applying convergent parallel mixed methods design to investigate medication adherence among people living with HIV in resource-limited settings: methodological insights from Ghana.Frontiers in public health · 2026Article
- Anaemia in pregnancy: A survey of prevalence and associated factors in Vhembe District, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025Article
- 'And the stick to fight TB is TPT': nurse-identified barriers and facilitators of tuberculosis preventive therapy implementation in rural South Africa.BMJ open respiratory research · 2025Article
- HIV Infection in Portugal: Measuring the Time Between Linkage to Care and Antiretroviral Therapy Initiation.Healthcare (Basel, Switzerland) · 2025Article
- The development and validation of the irrational beliefs scale for people living with HIV.BMC public health · 2025Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to identify the range and frequency of patient-reported barriers and facilitators to antiretroviral treatment (ART) adherence in sub-Saharan Africa (SSA).
designStudies from 2005 to 2016 were identified by searching 10 electronic databases and through additional hand and web-searching.
methodsInclusion criteria were HIV-positive adults taking ART based in any SSA country, qualitative study or quantitative survey and included at least one patient-reported barrier or facilitator to ART adherence. Exclusion criteria were only including data from treatment-naive patients initiating ART, only single-dose treatment, participants residing outside of SSA and reviews.
resultsAfter screening 11 283 records, 154 studies (161 papers) were included in this review. Forty-three barriers and 30 facilitators were reported across 24 SSA countries. The most frequently identified barriers across studies were forgetting (n = 76), lack of access to adequate food (n = 72), stigma and discrimination (n = 68), side effects (n = 67) and being outside the house or travelling (n = 60). The most frequently identified facilitators across studies were social support (n = 60), reminders (n = 55), feeling better or healthier after taking ART (n = 35), disclosing their HIV status (n = 26) and having a good relationship with a health provider (n = 22).
conclusionThis review addresses the gap in knowledge by collating all the patient-reported barriers and facilitators to ART adherence in SSA. Current barriers measures need to be adapted or new tools developed to include the wide variety of factors identified. The factors that have the greatest impact need to be isolated so interventions are developed that reduce the barriers and enhance the facilitators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.