ArticleInvestigative radiology2017
Ultrasound Tomography Evaluation of Breast Density: A Comparison With Noncontrast Magnetic Resonance Imaging.
Article in Investigative radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Adjunct Automated Breast Ultrasound in Mammographic Screening: A Systematic Review and Meta-Analysis.Journal of imaging · 2025Review
- Transcranial ultrasound tomography for brain imaging: Ex vivo results and potential for stroke imaging.Medical physics · 2025Article
- Prediction of mammographic breast density based on clinical breast ultrasound images using deep learning: a retrospective analysis.Lancet regional health. Americas · 2025Article
- Breast Tomographic Ultrasound: The Spectrum from Current Dense Breast Cancer Screenings to Future Theranostic Treatments.Tomography (Ann Arbor, Mich.) · 2024Review
- Radiological Features of Male Breast Neoplasms: How to Improve the Management of a Rare Disease.Diagnostics (Basel, Switzerland) · 2024Article
- Spatial and channel attention-based conditional Wasserstein GAN for direct and rapid image reconstruction in ultrasound computed tomography.Biomedical engineering letters · 2024Article
- From bedside to portable and wearable: development of a conformable ultrasound patch for deep breast tissue imaging.Molecular oncology · 2023Article
- Ultrasound and Photoacoustic Imaging of Breast Cancer: Clinical Systems, Challenges, and Future Outlook.Journal of clinical medicine · 2022Review
- Rapid Reductions in Breast Density following Tamoxifen Therapy as Evaluated by Whole-Breast Ultrasound Tomography.Journal of clinical medicine · 2022Article
- The Potential Role of the Fat-Glandular Interface (FGI) in Breast Carcinogenesis: Results from an Ultrasound Tomography (UST) Study.Journal of clinical medicine · 2021Article
- Multicenter Study of Whole Breast Stiffness Imaging by Ultrasound Tomography (SoftVue) for Characterization of Breast Tissues and Masses.Journal of clinical medicine · 2021Article
- Breast Acoustic Parameter Reconstruction Method Based on Capacitive Micromachined Ultrasonic Transducer Array.Micromachines · 2021Article
- The concordance in lesion detection and characteristics between the Anatomical Intelligence and conventional breast ultrasound Scan method.BMC medical imaging · 2021Article
- Amplitude based segmentation of ultrasound echoes for attenuation coefficient estimation.Ultrasonics · 2021Article
- Using Whole Breast Ultrasound Tomography to Improve Breast Cancer Risk Assessment: A Novel Risk Factor Based on the Quantitative Tissue Property of Sound Speed.Journal of clinical medicine · 2020Article
- Quantitative assessment of breast density using transmission ultrasound tomography.Medical physics · 2019Article
- Speed of sound ultrasound: a pilot study on a novel technique to identify sarcopenia in seniors.European radiology · 2019Article
- Transmission-reflection optoacoustic ultrasound (TROPUS) computed tomography of small animals.Light, science & applications · 2019Article
- Breast-density assessment with hand-held ultrasound: A novel biomarker to assess breast cancer risk and to tailor screening?European radiology · 2018Article
- Automated breast ultrasound: basic principles and emerging clinical applications.La Radiologia medica · 2018Review
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10 authors.
Funding
Abstract
objectivesUltrasound tomography (UST) is an emerging whole-breast 3-dimensional imaging technique that obtains quantitative tomograms of speed of sound of the entire breast. The imaged parameter is the speed of sound which is used as a surrogate measure of density at each voxel and holds promise as a method to evaluate breast density without ionizing radiation. This study evaluated the technique of UST and compared whole-breast volume averaged speed of sound (VASS) with MR percent water content from noncontrast magnetic resonance imaging (MRI). MATERIALS AND
methodsForty-three healthy female volunteers (median age, 40 years; range, 29-59 years) underwent bilateral breast UST and MRI using a 2-point Dixon technique. Reproducibility of VASS was evaluated using Bland-Altman analysis. Volume averaged speed of sound and MR percent water were evaluated and compared using Pearson correlation coefficient.
resultsThe mean ± standard deviation VASS measurement was 1463 ± 29 m s (range, 1434-1542 m s). There was high similarity between right (1464 ± 30 m s) and left (1462 ± 28 m s) breasts (P = 0.113) (intraclass correlation coefficient, 0.98). Mean MR percent water content was 35.7% ± 14.7% (range, 13.2%-75.3%), with small but significant differences between right and left breasts (36.3% ± 14.9% and 35.1% ± 14.7%, respectively; P = 0.004). There was a very strong correlation between VASS and MR percent water density (r = 0.96, P < 0.0001).
conclusionsUltrasound tomography holds promise as a reliable and reproducible 3-dimensional technique to provide a surrogate measure of breast density and correlates strongly with MR percent water content.
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