Evidence map›Paper›PMID 28121215›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Heterogeneous propagation of spreading depolarizations in the lissencephalic and gyrencephalic brain.

Edgar Santos, Renán Sánchez-Porras, Oliver W Sakowitz, Jens P Dreier, Markus A Dahlem

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  6. Collateral is brain: Low perfusion triggers spreading depolarization and futile reperfusion after acute ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
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  13. Physiological variables in association with spreading depolarizations in the late phase of ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Observational
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  19. Neurovascular mechanisms of migraine and cluster headache.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Edgar Santos1 Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Renán Sánchez-Porras1 Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Oliver W Sakowitz1 Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Jens P Dreier3 Center for Stroke Research Berlin, Charité University Medicine Berlin, Berlin, Germany.
Markus A Dahlem4 Department of Physics, Humboldt University of Berlin, Berlin, Germany.
University Hospital Heidelberg · DECharité - Universitätsmedizin Berlin · DEHeidelberg University · DEHumboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the recently published article, "Heterogeneous incidence and propagation of spreading depolarizations," it is shown, in vivo and in vitro, how KCl-induced spreading depolarizations in mouse and rat brains can be highly variable, and that they are not limited, as once thought, to a concentric, isotropic, or homogenous depolarization wave in space or in time. The reported results serve as a link between the different species, and this paper contributes to changing the way in which SD expansion is viewed in the lissencephalic brain. Here, we discuss their results with our previous observations made in the gyrencephalic swine brain, in computer simulations, and in the human brain.

Indexed as

BrainCortical Spreading DepressionAnimalsHumansMiceSwineanimal modelsgyrencephalic brainintrinsic optical signal imaginglissencephalic brainSpreading depolarization

Identifiers

PMID28121215
PMCPMC5531357
OpenAlexW2580706689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.