Evidence map›Paper›PMID 28121161›Full record

ArticleAIDS research and human retroviruses2017

Regulatory T Cell Effect on CD8

Lauren M Lepone, Giovanna Rappocciolo, Paolo A Piazza, Diana M Campbell, Frank J Jenkins, Charles R Rinaldo

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Is Kaposi sarcoma a novel comorbidity of cutaneous lymphoma? A systematic review of the literature.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Pooled it
  2. Trial
  3. Review
  4. An expanded population of CD8Frontiers in cell and developmental biology · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Lack of CD8Oncotarget · 2020
    Article
  10. Review
  11. The Binary Classification Of Chronic Diseases.Journal of inflammation research · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lauren M Lepone1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
Giovanna Rappocciolo1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
Paolo A Piazza1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
Diana M Campbell1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
Frank J Jenkins1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
Charles R Rinaldo1 Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania.
University of Pittsburgh · US

Funding

Validation, CLIA and Qualification (VQC): Enhancing the RS ratio as a tool for AIDS Clinical Trial Group (ACTG) tuberculosis trialsUM1AI106701 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$116.8M
University of Pittsburgh Multicenter AIDS Cohort Study (MACS)U01AI035041 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTINSON, JEREMY JAMES, RINALDO, CHARLES R · 1993 to 2018
$71.4M
Center for the Analysis & Management of the Multicenter AIDS Cohort StudyUM1AI035043 · NIAID · JOHNS HOPKINS UNIVERSITY · PI D'SOUZA, GYPSYAMBER, JACOBSON, LISA P · 2012 to 2018
$20.7M
CYTOTOXIC T CELL RESPONSES TO HHV8R01CA082053 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RINALDO, CHARLES R · 1999 to 2013
$5.2M
PITT AIDS RESEARCH TRAINING PROGRAMT32AI065380 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BARRATT-BOYES, SIMON M · 2005 to 2020
$3.2M
NCI NIH HHS R01 CA082053NIAID NIH HHS T32 AI065380NIAID NIH HHS U01 AI035041NIAID NIH HHS UM1 AI035043NIAID NIH HHS UM1 AI106701
6 · The paper itself

Abstract

We assessed CD8

Indexed as

AdultAntigens, ViralCD8-Positive T-LymphocytesHerpesviridae InfectionsHerpesvirus 8, HumanHumansInterferon-gammaMaleMiddle AgedProspective StudiesSarcoma, KaposiT-Lymphocytes, RegulatoryYoung AdultAntigens, ViralInterferon-gammaHIV/AIDS pathogenesisimmune responseT cell immunityT cells

Identifiers

PMID28121161
PMCPMC5512339
OpenAlexW2594447720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.