Evidence map›Paper›PMID 28121065›Full record

ArticleAdvanced healthcare materials2017

Chitosan-Gated Magnetic-Responsive Nanocarrier for Dual-Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy.

Hui Wang, Qingxin Mu, Richard Revia, Kui Wang, Xuezhe Zhou, Peter J Pauzauskie, Shuiqin Zhou, Miqin Zhang

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui WangDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Qingxin MuDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Richard ReviaDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Kui WangDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Xuezhe ZhouDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Peter J PauzauskieDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Shuiqin ZhouDepartment of Chemistry, The College of Staten Island, City University of New York, Staten Island, NY, 10314, USA.
Miqin ZhangDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.

Funding

Multifunctional nanoparticles to improve treatment of human glioblastomaR01CA161953 · NCI · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2013 to 2017
$1.7M
NCI NIH HHS R01 CA161953
6 · The paper itself

Abstract

A dual-layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on-demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic-thermal and chemotherapy.

Indexed as

ChitosanDrug CarriersMagnetic FieldsMagnetic Resonance ImagingNanoparticlesTomography, Optical CoherenceAnimalsCell Line, TumorHumansMiceChitosanDrug Carrierschitosan valvedrug carriersmultimodal imagingon/off releasesynergistic therapy

Identifiers

PMID28121065
PMCPMC5510588

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.