Evidence map›Paper›PMID 28120468›Full record

ReviewMicrocirculation (New York, N.Y. : 1994)2017

Neutrophil-mediated vascular barrier injury: Role of neutrophil extracellular traps.

Jamie E Meegan, Xiaoyuan Yang, Danielle C Coleman, Melanie Jannaway, Sarah Y Yuan

Open access · greenAbstract readReview
In one paragraph

Review in Microcirculation (New York, N.Y. : 1994), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Neutrophil Extracellular Traps Affect Human Inner Ear Vascular Permeability.International journal of molecular sciences · 2024
    Article
  14. Targeting neutrophils: Mechanism and advances in cancer therapy.Clinical and translational medicine · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Neutrophils and the Systemic Inflammatory Response Syndrome (SIRS).International journal of molecular sciences · 2023
    Review
  19. Review
  20. Skewing cPLAScience signaling · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jamie E MeeganDepartment of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa, FL, USA.ORCID 0000-0002-2644-676X
Xiaoyuan YangDepartment of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa, FL, USA.
Danielle C ColemanDepartment of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa, FL, USA.
Melanie JannawayDepartment of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa, FL, USA.
Sarah Y YuanDepartment of Molecular Pharmacology and Physiology, University of South Florida College of Medicine, Tampa, FL, USA.
University of South Florida · US

Funding

Microvascular Barrier Dysfunction in Thermal TraumaR01HL070752 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI YUAN, SARAH Y · 2002 to 2018
$4.7M
Neutrophil Activation and Microvascular HyperpermeabilityR01HL126646 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI YUAN, SARAH Y · 2016 to 2019
$1.5M
NHLBI NIH HHS R01 HL070752NHLBI NIH HHS R01 HL126646
6 · The paper itself

Abstract

Neutrophils play an essential role in host defense against infection or injury. While neutrophil activation is necessary for pathogen clearance and tissue repair, a hyperactive response can lead to tissue damage and microcirculatory disorders, a process involving complex neutrophil-endothelium cross talk. This review highlights recent research findings about neutrophil-mediated signaling and structural changes, including those induced by neutrophil extracellular traps, which ultimately lead to vascular barrier injury.

Indexed as

Neutrophil ActivationAnimalsEndothelium, VascularExtracellular TrapsHumansMicrocirculationNeutrophilsReceptor Cross-TalkSignal Transductionendothelial barrier dysfunctionneutrophil extracellular trapsvascular hyperpermeability

Identifiers

PMID28120468
PMCPMC5404986
OpenAlexW2581644694

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.