Evidence map›Paper›PMID 28120260›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2017

Evaluation of a Premixed Insulin Analog Suspension in Japanese People with Type 2 Diabetes and the Clinical Importance of Improved Injection Techniques: A Cross-Sectional Pilot Study.

Kunihiro Suzuki, Chie Aoki, Kanako Kato, Masanori Shimizu, Shintaro Sakurai, Kazunori Yanagi, Hisamoto Kuroda, Yoshimasa Aso

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In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kunihiro SuzukiDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan. kuni-s@dokkyomed.ac.jp.ORCID http://orcid.org/0000-0002-1287-304X
Chie AokiDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Kanako KatoDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Masanori ShimizuDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Shintaro SakuraiDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Kazunori YanagiDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Hisamoto KurodaDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.
Yoshimasa AsoDepartment of Endocrinology and Metabolism, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Simotsugagun, Tochigi, 321-0293, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with type 2 diabetes, who live in Asian countries, often use premixed insulin analogs. However, if these solutions are insufficiently mixed prior to use, patients will receive inaccurate doses of intermediate- and/or short-acting insulin, which could affect diabetes control. This study aimed to determine whether insulin users were correctly resuspending premixed insulin analog solutions prior to use.

methodsWe investigated whether Japanese patients with type 2 diabetes were correctly resuspending their premixed insulin analog solutions by assessing the optical densities (ODs) of the solutions.

resultsAmong 476 patients who used premixed insulin analogs, we found that the ODs of residual insulin differed significantly from the control values, particularly for high-mix insulin suspensions.

conclusionOur findings suggest that patients should be educated about the importance of properly resuspending these insulin analog solutions prior to use.

trial registrationUniversity Hospital Medical Information Network (UMIN No. 000022329).

Indexed as

Diabetes controlOptical densityPremixed insulin analogsType 2 diabetes

Identifiers

PMID28120260
PMCPMC5380491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.