Evidence map›Paper›PMID 28120177›Full record

ArticleEJNMMI research2017

The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [

John C Dickson, Livia Tossici-Bolt, Terez Sera, Jan Booij, Morten Ziebell, Silvia Morbelli, Susanne Assenbaum-Nan, Thierry Vander Borght, Marco Pagani, Ozlem L Kapucu and 5 more

Abstract read
In one paragraph

Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Japanese multicenter database of healthy controls for [European journal of nuclear medicine and molecular imaging · 2018
    Article
  11. Article
  12. Validation of Optimum ROI Size forAsia Oceania journal of nuclear medicine & biology · 2018
    Article
  13. [EJNMMI physics · 2017
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

John C DicksonInstitute of Nuclear Medicine, University College London Hospital NHS Foundation Trust, 235 Euston Road, London, NW1 2BU, UK. john.dickson2@nhs.net.
Livia Tossici-BoltDepartment of Medical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Terez SeraDepartment of Nuclear Medicine and Euromedic Szeged, University of Szeged, Szeged, Hungary.
Jan BooijDepartment of Nuclear Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Morten ZiebellNeurobiology Research Unit, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Silvia MorbelliNuclear Medicine Unit, Department of Health Sciences, IRCCS San Martino-IST, University of Genoa, Genoa, Italy.
Susanne Assenbaum-NanDepartment of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
Thierry Vander BorghtNuclear Medicine Division, Université Catholique de Louvain, Mont-Godinne Medical Center, Louvain-la-Neuve, Belgium.
Marco PaganiInstitute of Cognitive Sciences and Technologies, CNR, Rome, Italy.
Ozlem L KapucuDepartment of Nuclear Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey.
Swen HesseDepartment of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
Koen Van LaereDivision of Nuclear Medicine, University Hospital and K.U. Leuven, Leuven, Belgium.
Jacques DarcourtNuclear Medicine, Centre Antoine Lacassagne and University Hospital, Université de Nice de Sophia Antipolis, Nice, France.
Andrea VarroneDepartment of Clinical Neuroscience Psychiatry Section, Karolinska Institute, Stockholm, Sweden.
Klaus TatschDepartment of Nuclear Medicine, Municipal Hospital of Karlsruhe Inc., Karlsruhe, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of a normal database for [

resultsThere were no significant differences in the age-independent quantitative assessment of scan normality across reconstructions, system characterisation and quantitative methods (ROC AUC 0.866-0.924). With BRASS quantification, there were no significant differences between the values of sensitivity (67.4-83.7%) or specificity (79.4-91.2%) across all reconstruction and calibration strategies. However, the Southampton method showed significant differences in sensitivity between ACSC (90.7%) vs IRNC (76.7%) and FBP (67.4%) reconstructions with calibration. Sensitivity using ACSC reconstruction with this method was also significantly better with calibration than without calibration (65.1%). Specificity using the Southampton method was unchanged across reconstruction and calibration choices (82.4-88.2%).

conclusionsThe ability of a normal [

Indexed as

[123I]FP-CITDopamine transporterQuantificationReconstructionSPECT

Identifiers

PMID28120177
PMCPMC5265228

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.