Evidence map›Paper›PMID 28119856›Full record

ArticleFrontiers in cellular and infection microbiology2016

Toll-Like Receptors 2 and 4 Cooperate in the Control of the Emerging Pathogen

Maykel A Arias, Llipsy Santiago, Santiago Costas-Ramon, Paula Jaime-Sánchez, Marina Freudenberg, Maria P Jiménez De Bagüés, Julián Pardo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Frontiers in cellular and infection microbiology · 2024
    Review
  2. Article
  3. Article
  4. The Role of Innate Immunity in Pulmonary Infections.BioMed research international · 2021
    Review
  5. Article
  6. The Role of Neutrophils in Brucellosis.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maykel A AriasCell Immunity in Cancer, Inflammation and Infection Group, Department of Biochemistry and Molecular and Cell Biology, Biomedical Research Centre of Aragon (CIBA), IIS Aragon, University of Zaragoza Zaragoza, Spain.
Llipsy SantiagoCell Immunity in Cancer, Inflammation and Infection Group, Department of Biochemistry and Molecular and Cell Biology, Biomedical Research Centre of Aragon (CIBA), IIS Aragon, University of Zaragoza Zaragoza, Spain.
Santiago Costas-RamonCell Immunity in Cancer, Inflammation and Infection Group, Department of Biochemistry and Molecular and Cell Biology, Biomedical Research Centre of Aragon (CIBA), IIS Aragon, University of Zaragoza Zaragoza, Spain.
Paula Jaime-SánchezCell Immunity in Cancer, Inflammation and Infection Group, Department of Biochemistry and Molecular and Cell Biology, Biomedical Research Centre of Aragon (CIBA), IIS Aragon, University of Zaragoza Zaragoza, Spain.
Marina FreudenbergMax-Planck Institute for Immunobiology and Epigenetics Freiburg, Germany.
Maria P Jiménez De BagüésUnidad de Producción y Sanidad Animal, Centro de Investigación y Tecnología Agroalimentaria, Instituto Agroalimentario de Aragón - IA2, CITA-Universidad de Zaragoza Zaragoza, Spain.
Julián PardoCell Immunity in Cancer, Inflammation and Infection Group, Department of Biochemistry and Molecular and Cell Biology, Biomedical Research Centre of Aragon (CIBA), IIS Aragon, University of ZaragozaZaragoza, Spain; Nanoscience Institute of Aragon, University of ZaragozaZaragoza, Spain; Aragon I+D FoundationZaragoza, Spain.
Universidad de Zaragoza · ESInstituto de Investigación Sanitaria Aragón · ESFundacion Agencia Aragonesa para la Investigacion y el Desarrollo · ESMax Planck Institute of Immunobiology and Epigenetics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptors (TLRs) recognize pathogen-derived molecules and play a critical role during the host innate and adaptive immune response.

Indexed as

AnimalsBrucellaBrucellosisDendritic CellsLiverMiceMice, KnockoutRodent DiseasesSpleenT-Lymphocytes, CytotoxicToll-Like Receptor 2Toll-Like Receptor 4Tlr2 protein, mouseTlr4 protein, mouseToll-Like Receptor 2Toll-Like Receptor 4Brucelladendritic cellsgranzyme Bmouse modeltoll-like receptors

Identifiers

PMID28119856
PMCPMC5220065
OpenAlexW2580044818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.