Evidence map›Paper›PMID 28119572›Full record

ArticleFrontiers in cellular neuroscience2016

Chronic Treatment with Anti-bipolar Drugs Down-Regulates Gene Expression of TRPC1 in Neurones.

Ting Du, Yan Rong, Rui Feng, Alexei Verkhratsky, Liang Peng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Neuronal Store-Operated Calcium Channels.Molecular neurobiology · 2023
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Ting DuLaboratory of Metabolic Brain Diseases, Institute of Metabolic Disease Research and Drug Development, China Medical University Shenyang, China.
Yan RongLaboratory of Metabolic Brain Diseases, Institute of Metabolic Disease Research and Drug Development, China Medical University Shenyang, China.
Rui FengLaboratory of Metabolic Brain Diseases, Institute of Metabolic Disease Research and Drug Development, China Medical University Shenyang, China.
Alexei VerkhratskyFaculty of Life Sciences, The University of ManchesterManchester, UK; Achucarro Center for Neuroscience, Basque Foundation for ScienceBilbao, Spain.
Liang PengLaboratory of Metabolic Brain Diseases, Institute of Metabolic Disease Research and Drug Development, China Medical University Shenyang, China.
China Medical University · CNAchucarro Basque Center for Neuroscience · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the brain, TRPC1 channels are abundantly expressed in neurones virtually in all regions; these proteins function as receptor-activated ion channels and are implicated in numerous processes, being specifically important for neurogenesis. Primary cultures of mouse cerebellar granule cell, cerebral cortical neurones, and freshly isolated neurones from

Indexed as

bipolar disordercarbamazepinelithium saltsneuroneSOCETRPC1 channelsvalproic acid

Identifiers

PMID28119572
PMCPMC5223735
OpenAlexW2568166103

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.