Evidence map›Paper›PMID 28119455›Full record

ArticleThe Journal of biological chemistry2017

Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue: IN VIVO METABOLIC TURNOVER ANALYSIS.

Hirofumi Nagao, Hitoshi Nishizawa, Takeshi Bamba, Yasumune Nakayama, Noriyoshi Isozumi, Shushi Nagamori, Yoshikatsu Kanai, Yoshimitsu Tanaka, Shunbun Kita, Shiro Fukuda and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. T-cadherin, a major adiponectin binding partner, suppresses ERK signaling in metabolic tissues.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Response of Primary Human Adipocytes to Fatty Acid Treatment.Journal of cellular and molecular medicine · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Bariatric surgery and dimethyl fumarate-induced lymphopenia in patients with multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Hirofumi NagaoFrom the Departments of Metabolic Medicine.
Hitoshi NishizawaFrom the Departments of Metabolic Medicine, hitoshin1127@endmet.med.osaka-u.ac.jp.
Takeshi BambaDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Yasumune NakayamaDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Noriyoshi IsozumiBio-system Pharmacology, and.
Shushi NagamoriBio-system Pharmacology, and.
Yoshikatsu KanaiBio-system Pharmacology, and.
Yoshimitsu TanakaFrom the Departments of Metabolic Medicine.
Shunbun KitaFrom the Departments of Metabolic Medicine.
Shiro FukudaFrom the Departments of Metabolic Medicine.
Tohru FunahashiFrom the Departments of Metabolic Medicine.
Norikazu MaedaFrom the Departments of Metabolic Medicine.
Eiichiro FukusakiDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Iichiro ShimomuraFrom the Departments of Metabolic Medicine.
Osaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is closely associated with various metabolic disorders. However, little is known about abnormalities in the metabolic change of obese adipose tissue. Here we use static metabolic analysis and

Indexed as

Citric Acid CycleMetabolome3T3-L1 CellsAdipose Tissue, WhiteAnimalsDiet, High-FatGlucoseGlutamatesLiverMaleMiceMice, Inbred C57BLMice, ObeseMuscle, SkeletalObesityGlucoseGlutamatesadipocyteadipose tissue metabolismglutamatemetabolomicsobesity

Identifiers

PMID28119455
PMCPMC5377766
OpenAlexW2581656109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.