Evidence map›Paper›PMID 28119429›Full record

ArticleMolecular cancer research : MCR2017

Novel Assay to Detect RNA Polymerase I Activity

Gunes Guner, Paul Sirajuddin, Qizhi Zheng, Baoyan Bai, Alexandra Brodie, Hester Liu, Taija Af Hällström, Ibrahim Kulac, Marikki Laiho, Angelo M De Marzo

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Gunes GunerDepartment of Pathology, Urology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Paul SirajuddinDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Qizhi ZhengDepartment of Pathology, Urology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Baoyan BaiDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Alexandra BrodieDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Hester LiuDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Taija Af HällströmInstitute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Ibrahim KulacDepartment of Pathology, Urology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Marikki LaihoDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland. ademarz@jhmi.edu mlaiho1@jhmi.edu.
Angelo M De MarzoDepartment of Pathology, Urology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. ademarz@jhmi.edu mlaiho1@jhmi.edu.
Finland University · FI

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
TRANSGENIC MODELS FOR PROSTATE CANCER AND AUTOIMMUNITYP50CA058236 · NCI · JOHNS HOPKINS UNIVERSITY · PI DENMEADE, SAMUEL R · 1992 to 2020
$43.9M
Dual High-Throughput Imaging Screen for Nucleolar Integrity and RNA TranscriptionR01CA172069 · NCI · JOHNS HOPKINS UNIVERSITY · PI LAIHO, MARIKKI · 2014 to 2016
$1.0M
Chemogenomic Profiling of a Novel RNA Polymerase I InhibitorR21CA193637 · NCI · JOHNS HOPKINS UNIVERSITY · PI LAIHO, MARIKKI · 2016 to 2017
$388k
NCI NIH HHS P30 CA006973NCI NIH HHS P50 CA058236NCI NIH HHS R01 CA172069NCI NIH HHS R21 CA193637
6 · The paper itself

Abstract

This report develops an analytically validated chromogenic

Indexed as

AdultAgedBranched DNA Signal Amplification AssayCell Line, TumorDNA, Ribosomal SpacerHumansIn Situ HybridizationMaleMiddle AgedProstateProstatic Intraepithelial NeoplasiaProstatic NeoplasmsRNA Polymerase IRNA, RibosomalDNA, Ribosomal SpacerRNA Polymerase IRNA, Ribosomal

Identifiers

PMID28119429
PMCPMC5802390
OpenAlexW2580377695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.