ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Electrical Microstimulation of the Pulvinar Biases Saccade Choices and Reaction Times in a Time-Dependent Manner.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 64 citations in OpenAlex.
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- Individual Pulvinar Neurons Integrate Cortical and Subcortical Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Pulvinar subdivisions and connectivity patterns across primate species: a comparative perspective.Frontiers in neuroanatomy · 2026Review
- Spectrotemporal signatures of driving- and modulatory circuits across cortical and subcortical networks.Frontiers in human neuroscience · 2026Article
- Stereotactic lesioning of cholinergic cells by injection of ME20.4 Saporin in the nucleus basalis of Meynert in a rhesus monkey (Macaca mulatta).Journal of neuropathology and experimental neurology · 2026Article
- Thalamic nuclei volume changes associated with cognitive and motor manifestations of Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Causal role for pulvinar burst firing in thalamo-cortical attention control.bioRxiv : the preprint server for biology · 2025Article
- Frequency Coding of Multisensory Integration in the Local Field Potentials of the Medial Pulvinar.The European journal of neuroscience · 2025Article
- Single-cell RNA sequencing reveals the potential role of Postn(+) fibroblasts in promoting the progression of myocardial fibrosis after myocardial infarction.Scientific reports · 2025Article
- Projection Motifs and Wiring Logic of Medial Pulvinar Thalamocortical Axons in the Marmoset Monkey.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit.Scientific reports · 2024Article
- Multiple focal pulvinar projection fields in the macaque cortex.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Using camera-guided electrode microdrive navigation for precise 3D targeting of macaque brain sites.PloS one · 2024Article
- Altered neural oscillations underlying visuospatial processing in cerebral visual impairment.Brain communications · 2023Article
- Response Selectivity of the Lateral Posterior Nucleus Axons Projecting to the Mouse Primary Visual Cortex.Frontiers in neural circuits · 2022Article
- Visual search performance in cerebral visual impairment is associated with altered alpha band oscillations.Neuropsychologia · 2021Article
- Disentangling the influences of multiple thalamic nuclei on prefrontal cortex and cognitive control.Neuroscience and biobehavioral reviews · 2021Review
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The pulvinar complex is interconnected extensively with brain regions involved in spatial processing and eye movement control. Recent inactivation studies have shown that the dorsal pulvinar (dPul) plays a role in saccade target selection; however, it remains unknown whether it exerts effects on visual processing or at planning/execution stages. We used electrical microstimulation of the dPul while monkeys performed saccade tasks toward instructed and freely chosen targets. Timing of stimulation was varied, starting before, at, or after onset of target(s). Stimulation affected saccade properties and target selection in a time-dependent manner. Stimulation starting before but overlapping with target onset shortened saccadic reaction times (RTs) for ipsiversive (to the stimulation site) target locations, whereas stimulation starting at and after target onset caused systematic delays for both ipsiversive and contraversive locations. Similarly, stimulation starting before the onset of bilateral targets increased ipsiversive target choices, whereas stimulation after target onset increased contraversive choices. Properties of dPul neurons and stimulation effects were consistent with an overall contraversive drive, with varying outcomes contingent upon behavioral demands. RT and choice effects were largely congruent in the visually-guided task, but stimulation during memory-guided saccades, while influencing RTs and errors, did not affect choice behavior. Together, these results show that the dPul plays a primary role in action planning as opposed to visual processing, that it exerts its strongest influence on spatial choices when decision and action are temporally close, and that this choice effect can be dissociated from motor effects on saccade initiation and execution.
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